Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxyzine and plaquenil Plaquenil causing muscle weakness Many people have nausea, stomach cramps, and diarrhea when they first start taking Plaquenil hydroxychloroquine. If you have heart, eye, liver conditions, or psoriasis, talk to your doctor to see if Plaquenil hydroxychloroquine is right for you. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Before using Plaquenil, tell your doctor if you are allergic to any drugs, or if you have psoriasis, porphyria, liver disease, alcoholism, or glucose-6-phosphate dehydrogenase G-6-PD deficiency. Take Plaquenil for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil tamoxifen symptoms reticulocytosis Plaquenil hydroxychloroquine sulfate dose, indications., Plaquenil Oral Uses, Side Effects, Interactions, Pictures, Warnings. Plaquenil for energy Dr. Clarke and colleagues explored the possible beneficial effect of combining antiestrogen therapies either tamoxifen, a selective estrogen receptor modulator SERM or fulvestrant, a selective estrogen receptor downregulator SERD and ER antagonist with hydroxychloroquine in orthotopic human breast cancer xenografts in mice. Hydroxychloroquine overcomes tamoxifen resistance in breast.. Plaquenil Uses, Dosage & Side Effects -. Eye screening for patients taking hydroxychloroquine Plaquenil®. Side Effects. Drug information provided by IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Other Interactions. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Plaquenil toxicity isn’t even in the top 10, or the top 100” if you’re looking at incidence, he said. “It’s a pretty rare thing.” Nevertheless, he urged doctors to master the Academy’s new guidelines, because the effects from chloroquine and hydroxychloroquine, when they do occur, are severe and often irreversible.