Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. This medication is used to kill the malaria parasites living inside red blood cells. What is hydroxychloroquine sulfate used to treat What is hydroxychloroquine is for Chloroquine egfr Therapeutic monitoring of chloroquine was carried out in pregnant women with confirmed laboratory and clinical malaria after administration of 10 mg/kg body weight of the drug at 0 and 24th hour. Pregnancy. There are no adequate and well-controlled studies evaluating the safety and efficacy of chloroquine in pregnant women; usage during pregnancy should be avoided except in prophylaxis or treatment of malaria when benefit outweighs potential risk to fetus. Lactation Dosages Chloroquine 1,500 mg base over 3 days twice during pregnancy or Chloroquine 600 mg loading dose followed by 300 mg orally once per week. Intermittant preventative treatment in pregnancy IPTp doses will be administered between weeks 20-28 and weeks 28-34 gestation, 4 weeks apart. Both drugs may be needed for a complete cure and to prevent the return of infection (relapse). In some cases, you may need to take a different medication (such as primaquine) to kill the malaria parasites living in other body tissues. Chloroquine in pregnancy Chloroquine MedlinePlus Drug Information, Aralen, Chloroquine phosphate chloroquine dosing. What is hydroxychloroquine used for arthritisPlaquenil reductionPlaquenil hydroxychloroquine sulfate It appears to be safe for use during pregnancy. Chloroquine is a member of the drug class 4-aminoquinoline. It works against the asexual form of malaria inside the red blood cell. Chloroquine was discovered in 1934 by Hans Andersag. Chloroquine - Wikipedia. Chloroquine for Malaria in Pregnancy - Full Text View.. Dose Optimization of Chloroquine by Pharmacokinetic Modeling.. It should be noted that radioactively-tagged chloroquine administered intravenously to pregnant, pigmented CBA mice passed rapidly across the placenta. It accumulated selectively in the melanin. Chloroquine phosphate is a 4-aminoquinolone that acts by inhibiting heme polymerase. 198 Chloroquine is well tolerated and in appropriate doses may be safely used by young children and pregnant women. 199 Transient nausea or vomiting is seen in a small proportion of individuals and may usually be reduced by taking the drug with food. Occasionally, headaches or blurred vision are reported. Chloroquine, although grouped with hydroxychloroquine in table 2 of this article, is not routinely used in the management of SLE either in or out of pregnancy due to increased tissue deposition and increased risk of retinal toxicity and of fetal abnormalities 10 - 11.