Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine pigmentation Chloroquine autophagy p62 Plaquenil cause fatigue Military use of chloroquine in honduras Irreversible retinal damage observed in some patients who had received hydroxychloroquine sulfate; significant risk factors for retinal damage include daily doses of hydroxychloroquine sulfate greater than 6.5 mg/kg 5 mg/kg base of actual body weight, durations of use greater than five years, subnormal glomerular filtration, use of some. Pigmentary lesions of a nonchoroidal origin represent reactive changes occurring in the retinal pigment epithelium RPE. Both hyperplastic and hypertrophic changes may result in any combination of increased pigmentation, increased number or increased size of the RPE cells. Toxoplasmosis causes these changes on either a congenital or acquired. Sep 15, 2014 Hydroxychloroquine sulfate HCQ, Plaquenil is an analogue of chloroquine CQ, an antimalarial agent, used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune disorders. Its use has been associated with severe retinal toxicity, requiring a discontinuation of therapy. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Retinal hypopigmentation discrete plaquenil Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Differential Diagnosis of Retinal Disease Hair loss plaquenilPlaquenil side effects can you drinkIncidence of alopecia with plaquenil Hydroxychloroquine or 250mg Chloroquine Dosage levels that can cause toxicity 6.5 mg/kg Hydroxychloroquine Plaquenil19 3 mg/kg Chloroquine Arlen With Plaquenil Plaquenil is manufactured in only a 200 mg tablet The typical dosage is either 200 or 400 mg per day 200 mg daily puts anyone under 68 pounds at risk1 Early Plaquenil Toxicity Detected without Bull’s Eye Maculopathy. Retinal toxicity associated with chronic exposure to.. Ask the Expert Plaquenil and Sjögren’s. Mar 01, 2011 Hydroxychloroquine Plaquenil, Sanofi-Aventis remains widely used in the treatment of various rheumatologic disorders. A small percentage of patients exposed to hydroxychloroquine will develop irreversible, and potentially progressive, retinal toxicity for which no effective treatment exists. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. It is now considered for new disease applications in diabetes, heart disease and adjunct cancer therapies 2. Hydroxychloroquine is an immunomodulating drug that is commonly used in treating collagen vascular diseases such as rheumatoid arthritis and systemic lupus erythematosus. It has the serious side effect that it can cause irreversible macular damage when used in toxic doses over enough time.