Researchers from Huntsman Cancer Institute (HCI) at the University of Utah have now come up with a potential new therapy for pancreatic cancer patients. The researchers have found that a new combination therapeutic approach can effectively fight the disease and prolong survival among patients. Is plaquenil with robaxin 500 mg Plaquenil antiplatelet Dabrafenib, Trametinib and Hydroxychloroquine in Patients With Advanced BRAF Mutant Melanoma Study Purpose The primary purpose of this study is to determine the maximum tolerated dose MTD and preliminary safety of hydroxychloroquine HCQ when administered in conjunction with oral dabrafenib and trametinib D+T in patients with advanced BRAF mutant melanoma. Apr 10, 2019 Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Dabrafenib, Trametinib and Hydroxychloroquine in Patients With Advanced BRAF Mutant Melanoma BAMM The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. The results of the study were published in the latest issue of the journal The team has opened up the therapy for clinical trials at HCI as well as other centres across United States along with support from University of California, San Francisco, and Columbia University in New York. The therapy has shown promise in the laboratory set up and now is ready for use among human patients in its clinical trials. Trametinib and hydroxychloroquine Mekinist trametinib dosing, indications, interactions., Plaquenil Uses, Dosage & Side Effects - Skin side effects of plaquenil Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Hydroxychloroquine Plaquenil Side Effects & Dosage for.. Dabrafenib, Trametinib and Hydroxychloroquine in Patients.. Hydroxychloroquine Uses, Dosage & Side Effects -. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. Trametinib is a dual-kinase inhibitor that is used in the treatment of advanced malignant melanoma, usually in combination with darbafenib. Trametinib therapy is associated with transient elevations in serum aminotransferase and alkaline phosphatase levels during therapy, but has yet to be linked cases of clinically apparent acute liver injury. Fig. 4 Treatment of a pancreatic cancer patient with trametinib plus hydroxychloroquine T/HCQ led to a reduction in tumor marker cancer antigen 19-9 CA19-9 and overall tumor burden.