I've had RA for 5 years and took plaquenil for the first four years. Towards the end of that, I started having scalp rashes and lost a great deal of hair in patches. changed meds to Arava, which has caused severe skin irritation on my fingers, hands, and toes. What happens if i overdose on celecoxib and plaquenil None as far as i know i take plaquenil Plaquenil medication for lupus Chloroquine phosphate injection dosage Was the plaquenil controlling your RA symptoms? The trouble is you lose hair on Methotrexate too. But after losing heaps when I first went on it, I have stabalised now, I have thinner hair but it still looks fine and healthy. If plaq was working for your symptoms I'd go back on it. If you feel like the RA is escallating then go for mtx. Plaquenil is one of the firs line drugs and may or may not have side effects. MTX is more of a "chemo" medication and may or may not have side effects. I would encourage you to look at quality of life issues and go slowly if you are not in a hurry to squelch all of the discomfort of RA. Methotrexate vs plaquenil side effects long term and short term I was recently diagnosed with an autoimmune disease that mainly fuses my joints together, but causes severe pain and fatigue. The only problem is the Plaquenil causes severe headaches that interfer with my daily activities also. If plaq was working for your symptoms I'd go back on it. I was taken off of Arava yesterday, and now have the choice of plaquenil or MTX. I have had no responses, so maybe I should ask all of you out there who have been on both: If you knew plaquenil kept your RA symptoms pretty well controlled, but you were losing your hair on it, would you go back to the Plaquenil, or would you do the MTX? West Girl Post Edited (West Girl) : 11/4/2010 PM (GMT-6) Was the plaquenil controlling your RA symptoms? But after losing heaps when I first went on it, I have stabalised now, I have thinner hair but it still looks fine and healthy. Hydroxychloroquine vs methotrexate Chloroquine vs. Hydroxychloroquine for treating rheumatoid., Methotrexate or Plaquenil? DailyStrength Hydroxychloroquine 200 mg couponsPara ke sirve plaquenil terapyEye exam for plaquenil usePlaquenil cholesterol Plaquenil vs Methotrexate By Guest 1 post, last post over a year ago Dr Artem Agafonov answered this The Very Real Side Effects Of Modern Medications For Autoimmune Diseases, And What To Do About Them Plaquenil vs Methotrexate Antineoplastics Cancer drugs.. Methotrexate vs plaquenil side effects long term and short term. Hydroxychloroquine Reviews Everyday Health. Hydroxychloroquine rated 6.7/10 in overall patient satisfaction. Compare Hydroxychloroquine head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Hydroxychloroquine Compared to Alternatives - Hydroxychloroquine is an arthritis medication and an anti infectious agent. Methotrexate is an arthritis medication and a cancer medication. Dec 15, 2010 hello hope everyone is well just a quick question, i have been on methotrexate for 2 months increasing from 7.5 to 15 and now to 25mg.weekly now been given plaquenil 400mg daily, has anyone else been on this mixture and has it worked or how long should i wait to see if it works.