Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Plaquenil and magnesium Hydroxychloroquine dental side effects Hydroxychloroquine and prednisone are considered safe during pregnancy. Methotrexate and cyclophosphamide Cytoxan should not be used in pregnancy and should be discontinued for at least a. Hydroxychloroquine is a medication used to prevent and treat malaria and to treat autoimmune conditions such as rheumatoid arthritis or lupus. Hydroxychloroquine is sold under several brand names, including Plaquenil®. For more information on rheumatoid arthritis or lupus in pregnancy please see. The full risks of using Plaquenil hydroxychloroquine during pregnancy are not known at this time. This eMedTV segment includes more information on Plaquenil and pregnancy, and explains whether the drug is likely to affect a fetus. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Can you take hydroxychloroquine while pregnant How Rheumatoid Arthritis Affects Pregnancy, Hydroxychloroquine MotherToBaby Plaquenil and low blood pressureSeroqul and chloroquinHydroxychloroquine bone marrow suppressionPlaquenil for lupus dosage In animal studies on Plaquenil hydroxychloroquine and pregnancy, the medication crossed the placenta and accumulated in the eyes of the fetus when it was given to pregnant animals. Although human studies are lacking, available evidence suggests a relatively low risk to the fetus. Plaquenil and Pregnancy - Antibiotics Home Page. Plaquenil and Pregnancy - eMedTV Health Information.. Is it safe to take plaquenil hydroxychloroquine while.. If you have rheumatoid arthritis, talking to your doctor about hydroxychloroquine may be the right choice for your needs. The medication is generally well-tolerated, and has even been found safe overall for women who are pregnant or breastfeeding. How is This Medication Given? Doctors generally recommend regular eye exams while on Plaquenil, so that early changes can be caught. Once abnormalities are discovered, toxicity has already occurred. While it may be reversible if caught early, hydroxychloroquine retinopathy is not always reversible. Notify your eye doctor when you are on this medication so regular visual screening tests can be performed. If you are pregnant, considering becoming pregnant, or lactating, please discuss this with your doctor before taking this medication. However, hydroxycholorquine has been shown to be safe during pregnancy and breast feeding.