Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Hydroxychloroquine cost without insurance Does plaquenil suppress the immune system Plaquenil cost in canada Do you still have flare ups while taking hydroxychloroquine Multifocal Electroretinography mfERG Vision Testing. Multifocal ERG has been recognized as an effective test in helping doctors to diagnose and manage diseases affecting the retina, most notably retinal toxicities. 1-3 This visual electrophysiology technique is a test of localized retinal function through quasi-simultaneous stimulation of different areas of the retina. 4 The American Academy. A 57-year-old female presented to the Ophthalmology clinic at UIHC complaining bilateral central photopsias for the past two years. She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine Plaquenil 200mg bid 6.5mg/kg for 10 years, which was stopped one year prior to. This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Mferg plaquenil Multifocal ERG in Practice, Hydroxychloroquine Plaquenil Toxicity and. Plaquenil brand name costOptomolologist plaquenil eye exam montgomery al Don’t Drop Patients on Plaquenil. The other two are multifocal electroretinogram mfERG and fundus autofluorescence FAF. Why the change in the recommendations? Because “the risk of toxicity after years of Plaquenil use is higher than previously believed,” the study says. 1 Also. Don’t Drop Patients on Plaquenil - Review of Optometry. Hydroxychloroquine-Induced Retinal Toxicity - American.. Evaluating Hydroxychloroquine Toxicity With Multifocal.. Aetna considers multi-focal ERG mfERG medically necessary for detecting chloroquine Aralen and hydroxychloroquine Plaquenil toxicity. Aetna considers multi-focal ERG experimental and investigational for all other indications including the following not an all-inclusive list Diagnosis/evaluation of glaucoma Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity to various parts of the eye such as the cornea, ciliary body, and retina. Chloroquine can also induce cataract formation; however, no reports of hydroxychloroquine and cataract have been reported. This article focuses upon hydroxychloroquine retinopathy. Disease The Diopsys® mfERG vision test is a painless, safe, non-invasive way for your eye care provider to objectively measure the function of your retina – the light-sensitive layer at the back of your eye. When light from an image enters your eye, it is turned into electrical energy by cells in the retina.