One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Can methrotrexate be taken with plaquenile Plaquenil and neutropenia Medications of the chloroquine family, including chloroquine Nivaquine, Avloclor, hydroxychloroquine Plaquenil, and amodiaquine, have been associated with keratopathy Srinivasan et al. 2011. Quinolone antimalarial drugs are used in the prophylaxis and treatment of malaria as well as in the treatment of certain rheumatological disorders e. Indications Plaquenil Plaquenil under the instruction prescribed for juvenile and conventional rheumatoid arthritis, systemic, discoid lupus erythematosus. There are reviews of plaquenil successfully used for the treatment and prevention of acute attacks of malaria, provoked such strains Plasmodium vivax, malariae, ovale, falciparum. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil keratopathy Bullous keratopathy, Plaquenil - instructions, reviews, analogues Plaquenil eye testingVenus williams plaquenilDoxycycline plaquenil lyme Sub-epithelial deposition of other medications A good medical history should reveal the medication responsible. Amiodarone most commonly is the cause of vortex keratopathy, followed by CQ, HCQ, indomethacin, and phenothiazines. The appearance of the verticillata caused by these different medications is similar in appearance. Chloroquine And Hydroxychloroquine Toxicity - StatPearls.. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Hydroxychloroquine - Wikipedia. The adverse effects of HCQ have also been well documented and include neuromyotoxicity, cardiotoxicity and ocular toxicity. Ocular toxicity of HCQ ranges from a non-significant keratopathy to a potentially blinding retinopathy 6, 7. There has been uncertainty concerning the risk factors for ocular toxicity and the appropriate methodology for. Maculopathy, scotoma, vortex keratopathy, headache, accommodative dysfunction, whitening of eyelashes, phototoxicity3. Bull’s Eye Retinopathy. 400 mg of Plaquenil daily puts anyone under 135 pounds at a higher risk for toxicity To prevent reversible keratopathy, corneal exams twice yearly are recommended. Maculopathy is rare but should be screened for with biannual retinal examinations. REFERENCES. 1. Louis E, Belaiche J. Hydroxychloroquine Plaquenil for recurrence prevention of Crohn's disease after curative surgery. Gastroenterol Clin Biol 1995;3-4. 2.