It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Uses for hydroxychloroquine Generic name for plaquenil Hydroxychloroquine sulfate contraindications Pharmacokinetics of chloroquine Plaquenil is prescribed for Lupus, RA, Sjogren's Syndrome and Joint Pain and is mostly mentioned together with these indications. Interaction between Methotrexate and Plaquenil There is no known interaction between Methotrexate and Plaquenil in our records. However, an interaction may still exist. Learn about drug interactions between hydroxychloroquine and methotrexate and use the RxList drug interaction checker to check drug combinations. Drugs A-Z Pill Identifier Supplements Symptom Checker Diseases Dictionary Media Does Plaquenil Interact with other Medications? Severe Interactions. These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Interactions between plaquenil and methotrexate Hydroxychloroquine oral and methotrexate sodium oral Drug., Hydroxychloroquine and methotrexate Drug Interactions - RxList Chloroquine transfection calcium phosphate Renal failure and certain drug interactions such as interactions with tamoxifen, glycosides, methotrexate and ciclosporin can influence the pharmacokinetics of hydroxychloroquine and chloroquine. Mechanisms of action of hydroxychloroquine and chloroquine.. Plaquenil Oral Interactions with Other Medication. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Drug Interactions between methotrexate and Plaquenil. This report displays the potential drug interactions for the following 2 drugs Interactions between your drugs. Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Hydroxychloroquine sulfate Plaquenil ® can potentially interact with a few other medications. Some of these medicines that may lead to hydroxychloroquine drug interactions include Certain beta blockers, such as Bisoprolol Zebeta ® Metoprolol Lopressor ®, Toprol XL ® Propranolol Inderal ® Sotalol Betapace ® Timolol Blocadren ® Hydroxychloroquine oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To help avoid interactions, your doctor should manage all of your medications carefully.