White blood cells are an important part of your immune system, helping your body to fight off diseases and infections. If you have too few white blood cells, you have a condition known as leukopenia. Chloroquine treats which plasmodiums Plaquenil and eye floaters Pics of corneal chloroquine toxicity Because renal clearance of hydroxychloroquine does not correlate with creatinine clearance, dosage adjustments are not required in patients with renal impairment. However, a dosage reduction may be necessary in patients with renal disease or in patients with concomitant medications known to affect the kidney. Linda, any type of quinine drug can cause mast cells to degranulate, which will provoke an allergic-like reaction. Along with Allegra, you might want to try a mast-cell stabilizer. Quercetin is a natural stabilizer you can try in a supplement, but there are also rx meds. Or you might just be allergic to Plaquenil. Good luck figuring it out! Dec 12, 2018 Read medical definition of Leukopenia. Leukopenia A shortage of white blood cells. SLIDESHOW Hyperthyroidism Symptoms and Treatment See Slideshow If your blood is low in neutrophils, you have a type of leukopenia known as neutropenia. There are several different types of leukopenia, depending on which type of white blood cell your blood is low in: Each type protects your body from different kinds of infections. Does hydroxychloroquine cause leukopenia Plaquenil hydroxychloroquine sulfate dosing, indications., Terrible Itching on Plaquenil---PLEASE HELP. Plaquenil freeChloroquine in amoebiasisCompare hydroxychloroquine pricesWhat labs are needed for plaquenilChloroquine for malaria treatment Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Plaquenil Side Effects Common, Severe, Long Term -. Definition of Leukopenia. Hydroxychloroquine DermNet NZ. May 02, 2018 Another study found that titrating doses to target therapeutic blood concentrations can reduce disease activity in cutaneous lupus erythematosus. 25 Measuring the blood concentration of hydroxychloroquine is not common in clinical practice but may have a role in select patients in whom initial therapy using a standard dosing regimen does not. If any severe blood disorder such as aplastic anemia, agranulocytosis, leukopenia, or thrombocytopenia, appears which is not attributable to the disease under treatment, consider discontinuation of Plaquenil. Plaquenil should be administered with caution in patients having glucose-6-phosphate dehydrogenase G-6-PD deficiency. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes.