The clinical trials on this list are studying Hydroxychloroquine. NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. Plaquenil and gabapentin What are the symptoms of withdrawal from plaquenil Jun 22, 2018 Pancreatic cancer is associated with a hypercoagulable state resulting in a high risk of venous thromboembolism VTE, which affects up to 40% of patients during their course of disease 1,2,3. Development of VTE in patients with pancreatic cancer is associated with a poor prognosis 4, 5. Jan 31, 2019 Huntsman Cancer Institute, University of Utah Photo National Cancer Institute Investigators at the Huntsman Cancer Institute at the University of Utah are conducting a Phase I clinical trial to study the side effects and best dose of hydroxychloroquine when given together with trametinib MEKINIST ®, Novartis in treating patients with pancreatic cancer that has spread to nearby tissue, lymph nodes, or other places in the body and cannot be removed by surgery. Mar 14, 2012 When scientists administered hydroxychloroquine, an anti-malarial drug, together with known cancer drugs, they found it stopped the growth of cancerous tumors in two-thirds of the patients. Scientists know that human cancer cells grow by getting energy from adjacent tumors, where cells have begun to self-destruct. Talk to your doctor for help in deciding if one is right for you. You may want to think about taking part in a clinical trial. Hydroxychloroquine pancreatic cancer Phase II and pharmacodynamic study of autophagy inhibition., Phase I Study of Trametinib and Hydroxychloroquine in. Symptoms of allergic reaction to plaquenilHydroxychloroquine and hearing lossEczema plaquenilMacrobid and plaquenil Along the lines of the Trial Watch series published on a monthly basis in OncoImmunology,35 -38 here we summarize the dual role of autophagy in oncogenesis and tumor progression and discuss recent clinical trials investigating the use of chloroquine CQ, hydroxychloroquine HCQ in cancer patients. Chloroquine and hydroxychloroquine for cancer therapy. Researches Say Hydroxychloroquine Can Help Treat Cancer.. Trametinib and Hydroxychloroquine in Treating Patients.. A case of advanced pancreatic cancer with remarkable response to thalidomide, celecoxib and gemcitabine 5 months ago Dose Escalation Trial of the Wee1 Inhibitor Adavosertib AZD1775 in Combination With Gemcitabine and Radiation for Patients With Locally Advanced Pancreatic Cancer The primary goal of the research study is to determine whether treating pancreatic cancer patients with hydroxychloroquine in combination with gemcitabine before surgery is safe. The secondary goal is to determine if this new treatment regimen can effectively treat pancreatic cancer. Hydroxychloroquine in Previously Treated Patients With Metastatic Pancreatic Cancer Hydroxychloroquine is approved for the treatment of non-cancerous illnesses such as rheumatoid arthritis and systemic lupus erythematous. Researchers in the laboratory have tested tumors from patients with pancreatic cancer and have discovered that they have certain pathways inside the cells that promote growth and survival of the tumor.