Many people find that they have unexplained bruising on legs and want to know what causes bruises to appear for no apparent reason. Some people also bruise more easily than others and a seemingly insignificant knock may leave a black and blue dark patch on their skin. Chloroquine powder Hydroxychloroquine and supporting supplements Hallucinations, seizures, and hearing loss are among the serious side effects of Plaquenil. This eMedTV Web page provides a more in-depth list of potentially dangerous reactions and explains when to report such problems to your doctor. Increased tendency to bruise is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months, also take medication Enbrel, and have Osteoporosis Jan 30, 2019 Unexplained bruising on legs can be alarming. While it may be normal if you bruise easily, it can also be a symptom of an underlying health condition. Learn why you're bruising on your legs and. For example, being in the sun too long, aging, or a vitamin deficiency can weaken small blood vessels near the skin’s surface. Random or unexplained bruising on legs can happen for a number of reasons. Plaquenil and unexplained bruising Unexplained Bruising on Your Body Causes and Treatments, Will you have Increased tendency to bruise with Plaquenil. Chloroquine tablets to buy asdaPlaquenil visual field defects Sep 13, 2019 Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur. Plaquenil Side Effects Common, Severe, Long Term -. Unexplained Bruising on Legs Why It Happens & When to Call a.. Bruising easily 7 possible causes. However, if these unexplained bruises begin to appear on the legs quite frequently, then there may be an underlying ailment that could be disrupting your circulation. This is especially concerning if your bruises take an especially long time to heal after they appear. Causes of Unexplained Bruising on Legs Unexplained bruising & other symptoms, no diagnosis. Fieryshade posted I've had issues lately with lots of unexplained bruises, particularly on my legs and thighs although I've had a few on my side and back. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA 1.