Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Hydroxychloroquine and dry mouth Chloroquine functional groups Hydroxychloroquine sulfate coupon Hydroxychloroquine-induced pigmentation lesions usually begin after a few months or years of treatment. When we compared our patients with the controls, we found no significant association with the duration of HCQ treatment or with the cumulative dose of HCQ. Summary Skin discoloration - bluish is found among people who take Plaquenil, especially for people who are female, 40-49 old, have been taking the drug for 2 - 5 years, also take medication Imuran, and have Epilepsy. I was diagnosed almost 2yrs ago with Lupus, SLE & subacute subcutaneous. The plaquenil made me lose my hair immediately. When it came back in most of it came in white which I read that the medicine can bleach your hair. Then last year I noticed areas on my legs that are brown or maybe it's that my skin has been bleached in areas and is very white. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Plaquenil side effects skin discoloration Plaquenil Side Effects Common, Severe, Long Term -, Will you have Skin discoloration - bluish with Plaquenil. Purpose of hydroxychloroquineChloroquine aralen is effective in treating the what stagePlaquenil dosage for discoid lupusHydroxychloroquine price increaseHydroxychloroquine sulfate tablets ip Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Plaquenil & skin discoloration -. Hydroxychloroquine and skin darkening Hi All. - LUPUS UK. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Skin rash; Serious Side Effects of Plaquenil. If you are taking Plaquenil long-term, such as for an autoimmune condition, your doctor should regularly check you for potential serious side effects.