The proposed mechanism is inhibition of CYP450 2D6 hepatic metabolism by hydroxychloroquine. In a randomized, double-blind, crossover study, seven healthy subjects with CYP450 2D6 extensive metabolizer phenotypes took 400 mg hydroxychloroquine or placebo twice daily for 8 days, and 100 mg metoprolol orally on the ninth day. Sulfasalazine and hydroxychloroquine rheumatoid arthritis What does plaquenil help Goodrx plaquenil Chloroquine autophagy lc3 There is a moderate interaction between Metoprolol and Plaquenil. You may want to consider another combination. Always consult your doctor before taking these medications together. Do not stop taking the medications without a physician's advice. Metoprolol is a cardiovascular medication. Drug interactions are reported among people who take Metoprolol succinate and Plaquenil together. This study is created by eHealthMe based on reports of 144 people who take Metoprolol succinate and Plaquenil from Food and Drug Administration FDA, and is updated regularly. eHealthMe has been monitoring drugs and supplements since 2008. Nov 08, 2014 The difference is that Metoprolol SUCCINATE slow-releases its dose over a 24-hour period, whereas, Metoprolol TARTRATE releases over a 12-hour period. so you can either take your entire daily dose, as succinate, once a day. or. you can take tartrate twice a day with each dose being half of the total daily milligrams you need. No adverse effects were reported and the clinical significance is unknown. Average metoprolol AUC increased by 65% and maximum plasma concentrations increased by 72%. Can plaquenil and metoprolol tartrate be taken together Metoprolol tartrate and Plaquenil drug interactions - eHealthMe, Metoprolol succinate and Plaquenil drug interactions. Hydroxychloroquine sulfate generic If you need 100mg of metoprolol a day then yes, it's fine. You can take up to 450mg of metoprolol per day, so it is within the dose range. Metoprolol tartrate & metoprolol er succinate taken.. Metoprolol succinate n tartrate? -. Can I take atenolol and metoprolol together? Antihypertensives Blood.. Drug interactions are reported among people who take Metoprolol tartrate and Plaquenil together. This study is created by eHealthMe based on reports of 288 people who take Metoprolol tartrate and Plaquenil from Food and Drug Administration FDA, and is updated regularly. eHealthMe has been monitoring drugs and supplements since 2008. Combining metoprolol tartrate with digoxin may cause a dangerously slow heart rate bradycardia. You may need to be monitored very closely if you take these medications together. In some cases, it is not recommended to combine metoprolol tartrate with digoxin. Research on the web says that Atenolol is much longer lasting than Metoprolol and suggests that Metoprolol Tartrate has to be taken twice a day. Atenolol only once ! Atenolol only once ! Strangle, again, my Cardiologist who issued a prescription for Atenolol upon my request to be allowed to try it is for 25 mg twice a day.