Chloroquine use in sle

Discussion in 'Canadian Pharmacy Drugs Online' started by trio123, 11-Mar-2020.

  1. asptrans New Member

    Chloroquine use in sle


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. Most physicians with experience in lupus agree that antimalarial treatments such as hydroxychloroquine Plaquenil, chloroquine Aralen or quinicrine Atabrine should be used long-term, year-after-year, in all lupus patients who can tolerate them. Chloroquine and hydroxychloroquine are drugs derived from the quinoline molecule. Both are used as antimalarial blood schizonticides, and hydroxychloroquine is also frequently used as an antirheumatic. Their mechanism of action is not entirely understood.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Chloroquine use in sle

    Hydroxychloroquine in SLE, Why are treatments that were developed for malaria now.

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  4. In SLE patients the cytokine levels were measured just before and three months after starting chloroquine treatment at a dose of 125 mg twice daily. Although the majority of SLE patients had a low systemic lupus activity measure SLAM index, the levels of IL-6, IL-18 and TNF-alpha were significantly higher than in the control group.

    • Chloroquine treatment influences proinflammatory cytokine..
    • Chloroquine and hydroxychloroquine – Knowledge for medical students and..
    • Hydroxychloroquine - Wikipedia.

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. ovale, and P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Aralen chloroquine is an antimalarial drug used for the treatment of malaria and extraintestinal amebiasis. Common side effects are reduced hearing, tinnitus, nausea, vomiting, and diarrhea. Dosage, drug interactions, and pregnancy and breastfeeding safety are provided. Chloroquine is an aminoquinoline used for the prevention and therapy of malaria. It is also effective in extraintestinal amebiasis and as an antiinflammatory agent for therapy of rheumatoid arthritis and lupus erythematosus.

     
  5. AlexBlin User

    The resource you are looking for (or one of its dependencies) could have been removed, had its name changed, or is temporarily unavailable. The Risk of Retinal Toxicity with Plaquenil Wrong Hydroxychloroquine Dose Is Common, Putting Eyes at Risk. Hydroxychloroquine toxicity - EyeWiki
     
  6. sundy Guest

    Chloroquine brands in India DrugsUpdate India Chloroquine brands in India - Arquin from Agron Remedies, Bitaquine from Bombay Tablet, C-Quin from Ikon, Cadiquin from Zy. Cadila, Chlorolex from Lexica, Chloroquine from Cadila Genstar, Clokit from Indoco Rem, Clokit Junior from Indoco Rem, Cloquin from Indoco Rem, Cloquin-DS from Indoco Rem, E-Mal from Themis Medicare, E-Vivax from Themis Medicare, Emquin from Merck, Emquin.

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