It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Hydroxychloroquine in breastfeeding Does plaquenil cause eye pain Plaquenil causing depression Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA. Plaquenil is the most common antimalarial drug given to treat lupus, and most physicians with experience in lupus agree that antimalarial treatments should be used long-term, year-after-year in all patients who can tolerate them. Learn why treatments that were developed for malaria are now used for lupus. Read the study This medication is also used, usually with other medications, to treat certain auto-immune diseases lupus, rheumatoid arthritis when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs DMARDs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Long term use of plaquenil for lupus Longer-Term Use of Plaquenil Protects Against Lupus Flares., Longer-Term Use of Plaquenil Protects Against Lupus Flares Lupus. Hydroxychloroquine dose based on weight and renal functionChloroquine vs hydroxychloroquine difference These medications may also prevent lupus from spreading to certain organs, such as the kidney and central nervous system your brain and spinal cord and may help to reduce flares by as much as 50%. Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus Center. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. For some people with very mild lupus, NSAIDs alone are enough to control symptoms. Antimalarial drugs. Hydroxychloroquine Plaquenil is used to treat malaria, and researchers have found that this drug also helps with lupus flares. These drugs work well with mild to moderate cases of lupus. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. While today it is used to treat autoimmune conditions, such as rheumatoid arthritis and lupus, it was originally used as an anti-malaria drug. Although they are uncommon, Plaquenil has side effects that may affect your eyes.