Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Aralen How does hydroxychloroquine help rheumatoid arthritis Hi i have sd there are skin problems that comes with sd dont know if u have that and i also have raynauds.i have been on plaquinil for years and i have skin irritations but was told by doctors its from the sd.u may want to ask ur doc about that but i do no most sd sufferers have skin probs.u have scleroderma? Jan 13, 2020 Skin discoloration - bluish is found among people who take Plaquenil, especially for people who are female, 40-49 old, have been taking the drug for 2 - 5 years, also take medication Imuran, and have Epilepsy Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. For people with skin problems This drug may. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil skin discoloration Drug-induced hyperpigmentation DermNet NZ, Will you have Skin discoloration - bluish with Plaquenil. Chloroquine phosphate suspension ipWill plaquenil cause weight lossThrombocytopenia plaquenilChloroquine for hpv Purpose Hydroxychloroquine HCQ is a systemic antimalarial used to treat cutaneous and systemic lupus erythematosus and other connective tissue diseases. Mucocutaneous hyperpigmentation is a well-documented side effect of HCQ that occurs in 10-25% of users. Lesions resemble ecchymoses that fail to resolve, and drug extravasation and binding to melanin is a theorized mechanism. Some cases are. Treatment of hydroxychloroquine-induced hyperpigmentation of.. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Will you have Skin discoloration - bluish with Plaquenil - eHealthMe. She presented 3 months later with multiple skin lesions predominantly on her neck, bilateral forearms, and dorsal feet. The skin lesions were macular or patchy, some well and others poorly demarcated, with a hyperpigmentation of gray to black discoloration, generally annular, but some with irregular morphology. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Plaquenil or hydroxychloroquine has been known to cause a darkened discoloration of skin and/or mucous membranes. This is considered an adverse reaction and should be discussed with your prescriber. It is important to evaluate this color change to make sure there is nothing else wrong.