Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Hydroxychloroquine cystic fibrosis Sierra leone chloroquine Indomethacin is a nonsteroidal anti-inflammatory drug NSAID that reduces fever, pain and inflammation. It is similar to ibuprofen Motrin and naproxen Naprosyn, Aleve. Indomethacin works by reducing the production of prostaglandins. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. What is Indomethacin? Indomethacin has active ingredients of indomethacin. It is often used in gout. Check the latest outcomes from 10,256 Indomethacin users, or browse all drugs. What is Plaquenil? Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Indocin and plaquenil Indomethacin vs Meloxicam Comparison -, Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis Visual field plaquenil A more chronic form of interstitial lung disease and fibrosis is also seen in patients with rheumatoid arthritis. This may be increased with methotrexate. Myelosuppression lowering of blood counts is also rare at the low doses of methotrexate utilized for rheumatoid arthritis. Patients at particular risk include those with renal insufficiency from other causes or use of trimethoprim Bactrim®, Septra® which increases levels of methotrexate. Rheumatoid Arthritis Treatment Options Johns Hopkins Arthritis Center. Indomethacin and Plaquenil drug interactions - eHealthMe. Calcium Pyrophosphate Deposition CPPD. A comprehensive guide to side effects including common and rare side effects when taking Rinvoq Upadacitinib Extended-release Tablets includes uses, warnings, and drug interactions. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Indomethacin is one of the most potent NSAIDs that has been associated with cases of corneal opacities and blurred vision, especially when used long term. 40 Symptoms associated with the corneal opacities can range from mild light sensitivity to frank photophobia. On slit lamp examination, the corneal lesions appear either as fine stromal speckled opacities or have a whorl-like distribution resembling chloroquine keratopathy.