Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Plaquenil safe in pregnancy Malarone vs chloroquine Hydroxychloroquine versus sulfasalazine Plaquenil method of action Feb 19, 2020 Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. OBJECTIVE The purpose of this study was to evaluate the efficacy and safety of a novel high-dose hydroxychloroquine regimen in patients with PCT. METHODS Sixty-five first episodes and 28 recurrent episodes of PCT were treated with hydroxychloroquine, 250 mg three times daily, for 3 days. Hydroxychloroquine is an antimalarial drug used to prevent and treat malaria. Hydroxychloroquine Plaquenil is also a disease-modifying anti-rheumatic drug DMARD used to treat both acute and chronic rheumatoid arthritis, systemic lupus erythematosus, and discoid lupus erythematosus. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Pct and hydroxychloroquine Hydroxychloroquine Professional Patient Advice -, High-dose hydroxychloroquine treatment of porphyria. Chloroquine resistente bakterien disserationPlaquenil and eye problems Porphyria cutanea tarda PCT is an iron-related disorder that responds to treatment by phlebotomy or low-dose hydroxychloroquine, but comparative data on these treatments are limited. The hypothesis is that hydroxychloroquine is noninferior to phlebotomy in terms of time to remission. Hydroxychloroquine and Phlebotomy for Treating Porphyria.. Hydroxychloroquine Plaquenil Success, Reviews and Side Effects. Hydroxychloroquine vs. phlebotomy for porphyria cutanea tarda. Porphyria cutanea tarda PCT is a rare disorder characterized by painful, blistering skin lesions that develop on sun-exposed skin photosensitivity. Affected skin is fragile and may peel or blister after minor trauma. Hydroxychloroquine and chloroquine are contraindicated in pregnant women or women who are lactating. These drugs are also. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more.