One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Plaquenil kills How does chloroquine prevent malaria Plaquenil low heart rate Plaquenil Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. It is now considered for new disease applications in diabetes, heart disease and adjunct cancer therapies 2. A risk factor for Plaquenil hydroxychloroquine retinotoxicity is a daily dose that exceeds 5.0 mg of drug per kg of body weight. The tool on the right simply calculates this threshold based on a ppatient’s real body weight. It’s important to understand that the daily dose is only one risk factor for plaquenil retinotoxicity. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil eye oct Plaquenil Related Eye Problems - Fraser Eye, Hydroxychloroquine Plaquenil Toxicity and Recommendations. Hydroxychloroquine and ldnHow long does it take plaquenil to workLong term use of hydroxychloroquine Aug 25, 2019 A spectral domain OCT is a device that shows the Eye Doctor all the cells of the retina and retinal pigment epithelium. The bright white lines at the bottom of the image are the part of the retina that can be damaged by Plaquenil. Plaquenil How I’m okay with it all — The Eye Doctor - Dr.. Plaquenil Risk Calculators. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. The presence of bull’s-eye maculopathy indicates the disease has been progressing for years, resulting in foveal thinning and likely vision loss. 8 SD-OCT is a highly sensitive and reproducible imaging modality used in the detection of Plaquenil retinal toxicity. The preferential loss of photoreceptor IS/OS junction makes SD-OCT an ideal tool to identify early changes associated with Plaquenil retinal toxicity. May 12, 2016 Plaquenil can prove toxic to the retina, threatening the vision. Regular eye examinations are essential for those patients taking plaquenil because over time the retina can become damaged beyond repair. Regular medical monitoring is the only way to ensure that toxicity is not occurring. Aug 01, 2009 A few years ago my eye doctor noticed an issue on the exam, and I noticed peripheral vision damage and glare issues. He immediately same day called my rheumatologist, who took me off plaquenil. My eye doc said it was the first case he had seen where there was an effect.