He had a history of rheumatoid arthritis, and had been treated with hydroxychloroquine for the last 8 years. Echocardiography revealed a left ventricular ejection fraction of 25%, with diffuse hypokinesis. Does plaquenil reduce inflammation Hydroxychloroquine iris Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. Plaquenil can cause serious liver or heart problems, especially if you use certain medicines at the same time, including other medicines to treat malaria; an antibiotic or antifungal medicine; antiviral medicine to treat hepatitis or HIV/AIDS; antidepressants or antipsychotic medicines; birth. Though serious heart muscle disease is not commonly caused by lupus, heart failure can occur if your heart does not have the strength to pump enough blood to the different tissues and organs. Endocarditis. The endocardium is the tissue that lines the inner walls of your heart and the valves that separate the heart’s different chambers. The differential diagnosis for new onset non-ischemic cardiomyopathy in this patient included inflammatory cardiomyopathy, viral myocarditis, sarcoidosis, amyloidosis, hemochromatosis, Fabry's disease and HCQ toxicity. Coronary angiography demonstrated non-obstructive coronary disease. Treatment was initiated with guideline directed medical therapy, and patient clinically improved. Plaquenil and heart issues Hydroxychloroquine-induced cardiomyopathy and heart failure., Plaquenil Uses, Dosage & Side Effects - Who manufactures sandoz plaquenilCcca plaquenilPlaquenil contraindicationsNifedipine and hydroxy chloroquine side effects One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. The Risk of Retinal Toxicity with Plaquenil. How lupus affects the heart and circulation Lupus Foundation of America. Rapid Heartbeat with Plaquenil - Lupus - MedHelp. Overdose symptoms may include drowsiness, vision changes, slow heart rate, chest pain, severe dizziness, seizure convulsions, or shallow breathing. What should I avoid while taking hydroxychloroquine Plaquenil, Plaquenil Sulfate, Quineprox? Find information about common, infrequent and rare side effects of Plaquenil Oral. ATLANTA – Hydroxychloroquine Plaquenil 400 mg/day starting by pregnancy week 10 reduces recurrence of congenital heart block in infants born to women with anti-Ro antibodies, according to an open-label, prospective study presented at the annual meeting of the American College of Rheumatology.