In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Retinal half life of plaquenil What does chloroquine treat In addition, an extensive review of the English literature has been performed regarding the association of antiestrogen therapy with autoimmune disorders. In conclusion, Oncologists should be aware of the potential development of autoimmune reactions in breast cancer patients treated with aromatase inhibitors. Importance Primary Sjögren syndrome is a systemic autoimmune disease characterized by mouth and eye dryness, pain, and fatigue. Hydroxychloroquine is the most frequently prescribed immunosuppressant for the syndrome. Health conditions that can cause hyperpigmentation Skin discolouration or hyperpigmentation is a sign of underlying health problems. Switch to हिंदी. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Plaquenil and hyperpigmentation sjogren's Persistent cutaneous hyperpigmentation due to hydroxychloroquinone one., Hydroxychloroquine for Sjögren Syndrome Symptoms Stop taking plaquenilChloroquine scheduled drugChloroquine to buyPlaquenil side effects dry skin Study Raises Questions about Sjogren's and Plaquenil Image Source For many patients with Sjogren's, Plaquenil hydroxychloroquine has long been the go to drug that their doctors prescribe. It is often the first line of attack before other more aggressive therapies are added such as methotrexate or rituximab that have bigger impacts on the. Study Raises Questions about Sjogren's and Plaquenil. Health conditions that can cause hyperpigmentation. Can Plaquenil cause Hyperpigmentation? - Page 2. I've been on Plaquenil about 2 months, and it has helped my knee/back pain, which is wonderful. I get the hyperpigmentation, too, but it is mostly on just my arms. Instead of brown spots, I get solid dark brown arms, but I have little spots on my arms with NO pigment, so there are white polka dots. Plaquenil and skin discoloration. SMF. It’s used in people with Sjogren’s syndrome, rheumatoid arthritis, and lupus to relieve joint pain, fatigue, and rashes. It may take up to 12 weeks for you to notice the effects of hydroxychloroquine. Hydroxychloroquine is safe, even for pregnant women with Sjogren’s syndrome. Cosmetic fillers are a popular anti-aging solution, but plastic surgeons and dermatologists will not administer this form of treatment for patients with autoimmune disease. Thyroid disease, lupus, rheumatoid arthritis and multiple sclerosis are common types of autoimmune disease.