In many cases, once the offending drug has been stopped, fading of the lesions occurs. However, the pigmentation may last a long time or become permanent. Symptoms of ete damage when taking hydroxychloroquine Plaquenil and cold medicine Plaquenil eye test Chloroquine pharmacodynamics We report two cases of hydroxychloroquine-induced hyperpigmentation presenting in a 50-year-old Caucasian female case 1 and a 78-year-old female case 2, both receiving 400 mg per day. Case 1 had an arthritis predominant undifferentiated connective tissue disease, which was treated with hydroxychloroquine for 4-5 years. Plaquenil and Skin hyperpigmentation - from FDA reports Summary Skin hyperpigmentation is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Omniscan, and have Arteriogram. Skin Hyperpigmentation with Hydroxychloroquine Hydroxychloroquine Plaquenil is a common trade name is an anti-inflammatory oral medication that is commonly used to treat many autoimmune diseases. In the hair clinic, we use it for diseases such as lichen planopilaris, frontal fibrosing alopecia, pseudopelade and discoid lupus. Skin, the largest organ of the human body, is a mirror of your health. Because many drugs that induce skin pigmentation also cause photosensitivity reactions, sun protection is usually recommended. Plaquenil associated hyperpigmentation Hydroxychloroquine Side Effects Common, Severe, Long Term., Will you have Skin hyperpigmentation with Plaquenil - eHealthMe Effects of plaquenil on skin Applies to hydroxychloroquine oral tablet Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Hydroxychloroquine Side Effects Common, Severe, Long Term -. Skin Pigmentation with Hydroxychloroquine Plaquenil.. Hydroxychloroquine-Induced Pigmentation in Patients With.. This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. Dec 15, 2017 One such sign is hyperpigmentation, a sign from your skin that all is not well within your body. Hyperpigmentation is a dermatological condition when the getting discoloured and darkened in places. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Deficiency Of Granulocytes A Type Of White Blood Cell.