Please review the following URL and make sure that it is spelled correctly. Hydroxychloroquine (Plaquenil) is considered a disease-modifying anti-rheumatic drug (DMARD). Plaquenil magnesium Chloroquine lupus erythematosus Chloroquine phosphate freshwater Plaquenil. Plaquenil hydroxychloroquine is a Disease Modifying Anti-Rheumatic Drug DMARD that is widely used to reduce inflammation pain and swelling in the treatment of many types of arthritis and lupus. Plaquenil is also known as a treatment for malaria, a blood-borne parasite spread by mosquitoes in many tropical and sub-tropical. Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. Brand names for prednisone include Deltasone, Rayos, and Prednisone Intensol. Plaquenil and belong to different drug classes. Plaquenil is an antimalarial medication and prednisone is a glucocorticoid. Side effects of Plaquenil and prednisone that are similar include nausea, vomiting, or headache. It may prevent joint damage and reduce the risk of long-term disability. It can decrease the pain and swelling of arthritis. Plaquenil prednisone Plaquenil Oral Uses, Side Effects, Interactions, Pictures., Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Plaquenil and radiation therapy toxiciy I have been on prednisone for 15 months and am down to 5 mg. I cannot seem to get below that dose without having a flate. My rheumatologist has started me on Plaquenil and has said this should help me get off the prednisone. He said he would rather see me on Plaquenil instead of prednisone due to less side effects of the Plaquenil. Plaquenil? I have been on prednisone for 15 months. - PMRGCAuk. Plaquenil vs. Prednisone Prescription Treatment for.. I'm using plaquenil hydroxychloroquine 200mg and.. Systemic lupus erythematosus is a disease that continues to evolve over time. Thus, a patient who presents with skin and joint disease remains at risk for renal disease even after having lupus. I started with plaquenil last year, yes it took almost 6 months to get a level in your body, it does help, trust me. I was on Prednisone 7.5 to 10 mg per day, had a bad flair up and I am on 40 mg per day, last Friday the dr.''s told me to go down by 5 mg per week, so from 40mg to 35 mg per day. I take both prednisone and plaquenil. I heard someone once say that prednisone is the drug one loves to hate. It really does wonders to control inflammation, but has nasty side effects when given in large doses and/or used for a long period of time.