I've stopped Sulfa as I was experiencing a bad taste & smell, which may be caused by sulfa. After a while it wasn't as effective and I too was prescribed methotrexate alongside. I'm about to start MTX & am hoping that I wont have side effects with that! The side effects of the methotrexate for me were horrendous (chronic chest infections) and I'm now asthmatic as a result. Chloroquine tablets asda Hydroxychloroquine sulfate and psoriasis Plaquenil and stroke How does hydroxychloroquine work in ra Plaquenil is an arthritis medication and an anti infectious agent. Sulfasalazine is an arthritis medication and an IBD medication. There may be a negative interaction between Plaquenil and alcohol. There may be a negative interaction between Sulfasalazine and alcohol. Compare Methotrexate vs Sulfasalazine head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Methotrexate rated 6.7/10 vs Sulfasalazine rated 5.7/10 in overall patient satisfaction. However, hydroxychloroquine has an extremely favorable toxicity profile and is widely considered to be safe to use in the perioperative period as it is not a potent immunosuppressant. Leflunomide, sulfasalazine, and azathiaprine all have immunosuppressive properties and can be toxic at high levels. I had side effects from MTX, which largely wore off, but haven't had any problems with the Hydroxy or Sulpha. I refuse to take it now even if its my passport to biologic treatment. I started with MTX which worked, but not enough so the others were added in which has been better. Plaquenil and sulfasalazine Hydroxychloroquine sulfate and Sulfasalazine drug interaction., Methotrexate vs Sulfasalazine Comparison - How effective is plaquenil for rheumatoid arthritisCan chloroquine cause abortionCan i use of hydroxychloroquine with sulfa allergyGuidelines for plaquenil screening Drug interactions are reported among people who take Sulfasalazine and Plaquenil together. This study is created by eHealthMe based on reports of 7,132 people who take Sulfasalazine and Plaquenil from Food and Drug Administration FDA, and is updated regularly. eHealthMe has been monitoring drugs since 2008. Sulfasalazine and Plaquenil drug interactions - eHealthMe. Perioperative Management of Medications Used in the.. Hydroxychloroquine Plaquenil RheumTutor. Hydroxychloroquine is sometimes combined with methotrexate for additive benefits for signs and symptoms or as part of a regimen of “triple therapy” with methotrexate and sulfasalazine. Mechanism The mechanism of action of antimalarials in the treatment of patients with rheumatoid arthritis is unknown but is thought to involve changes in. Sulfasalazine Azulfidine® is part of a class of medicines called sulfa drugs. It’s a mix of salicylate, which is the main ingredient in aspirin, and an antibiotic. Some people are allergic to all sulfa drugs, so they can’t take sulfasalazine Azulfidine®. Most people take two 500 mg tablets of sulfasalazine Azulfidine twice per day. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis.