It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Nifedipine and hydroxychloroquine What can you mix.with chloroquine for fish Who makes hydroxychloroquine I was dx in August with Lupus and my Rheumy said she was afraid to start me on Plaquenil since I had a bad reaction to a Sulfa antibiotic I took and the same reaction when a Dr gave me Lasix. I read that the sulfa in Plaquenil is different from those in antibiotics and most people with Lupus have an allergy to Sulfa but can take Plaquenil. Medications that are known to cause tinnitus or hearing loss are considered “ototoxic medications.” Discontinuing these medications can prevent tinnitus and hearing loss progression, though the ringing may not always go away. Check with your doctor before stopping the use of any medication. I have just spent my first month off my Plaquenil after over 15 years. My doctor is concerned about my retinas, no change yet, but my total use has been 1400 grams. The second week I was off, I developed shingles, caught it, took the medication and it went away. I also have been on methotrexate.4 ml/week. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Doctor took me off plaquenil after hearing loss and ringing PLAQUENIL To Take or Not To Take?" Lupus Community., Prescriptions That May Cause Ringing in the Ears Tinnitus - GoodRx Hydroxychloroquine 200 mg suspension They told me that plaquenil can cause it, but he did not think that it was that. So, anyway, after my appt. they determined that I have severe high frequency hearing loss and that is what is causing the ringing in my ears. If I had said something before they might have been able to help me more, but now there isn't anything that can be done. Plaquenil and tinnitus DailyStrength. My doctor has discontinued my plaquenil." Lupus Community - Support Group. Long-Term Side Effects of Plaquenil for Rheumatoid.. My rheumatologist took me off plaquenil 2 years ago; I still take 400 mg of ibuprofen 2X/week. I still get flares once or twice a year, but they are not as bad.6, as opposed to a 10, on the pain scale. Tinnitus started a few weeks after I started plaquenil & I still have it. It's vastly annoying, but at least it doesn't hurt! best of luck to. Sister has RA/niece has lupus. Currently taking 400 mg. Plaquenil daily, 20 mg. MTX weekly, leucovorin 10 mg. weekly. Eight years ago I had sudden, permanent hearing loss in my left ear with tinnitus starting soon after the loss. After 6 months on the above drugs I woke one night with very loud ringing in my good ear that lasted over 2 hrs. A case with reversible symmetrical sensorineural hearing loss following hydroxychloroquine therapy is described. A 57-year-old, human immunodeficiency virus HIV positive man was referred to the HIV clinic of Imam Khomeini Hospital, Tehran with chief.