It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Plaquenil lyme disease Chloroquine proguanil combination Plaquenil and pepto bismol Hydroxychloroquine is an arthritis medication and an anti infectious agent. Plaquenil is an arthritis medication and an anti infectious agent. There may be a negative interaction between Hydroxychloroquine and alcohol. There may be a negative interaction between Plaquenil and alcohol. Sorry to hear that you are having a lot of pain with your RA. I have lupus which mainly affects my joints and skin. I have been taking hydroxychloroquine which is the generic of plaquenil for the past three years. My rheumy recently added Imuran instead of methotrexate. Plaquenil hydroxychloroquine takes up to 3 months to begin working. A clinical study compared hydroxychloroquine 400 mg PO once daily vs. placebo in 101 patients over a period of 24 weeks. Significant improvements in joint score, pain, and grip strength but not erythrocyte sedimentation rate ESR were seen in the active drug group. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Hydroxyclorquine vs plaquenil Hydroxychloroquine Plaquenil and Hair Loss Is my Plaquenil., Arthritis Which would you pick and why? - Plaquenil or. How plaquenil helps lupus ph levels Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Plaquenil hydroxychloroquine sulfate dose, indications.. Plaquenil hydroxychloroquine sulfate dosing, indications.. Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Side Effects. Drug information provided by IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus.