It doesn't go away, but you can keep it under control. It could be triggered by other mouth problems such as having a rough crown or a habit of biting your cheeks or tongue. It’s a long-lasting disease that affects your mouth. It may also be a reaction to metal, such as dental fillings. Plaquenil and hair loss message boards How long do side effects of plaquenil last Hydroxychloroquine and allergy testing Eye screening for plaquenil Oral lichen planus is a chronic disease that causes painful patches inside the mouth. WebMD explains other symptoms, causes, and treatment. Feb 20, 2019 Lichen planus LIE-kun PLAY-nus is a condition that can cause swelling and irritation in the skin, hair, nails and mucous membranes. On the skin, lichen planus usually appears as purplish, itchy, flat bumps that develop over several weeks. Lichen planus LP is a rare, chronic, inflammatory autoimmune skin and mucous membrane disease. LP most commonly presents as itchy, shiny, reddish-purple spots lesions on the skin cutaneous LP or as white-gray lesions in the mouth or on the lips oral LP. Doctors aren't sure what causes oral lichen planus. With oral lichen planus, some doctors believe those cells get confused and attack the lining of your mouth. Other possible triggers include medicines like painkillers, high blood pressure treatments, diabetes drugs, and malaria medications. Lichen planus chloroquine Chloroquine - FDA prescribing information, side effects and uses, Lichen planus - Symptoms and causes - Mayo Clinic Nonbiological dmard antimalarial hydroxychloroquine plaquenilPlaquenil dilated eye retinal exam The exact cause of lichen planus is unknown. However, it is likely to be related to an allergic or immune reaction. Risks include Exposure to medications, dyes, and other chemical substances including gold, antibiotics, arsenic, iodides, chloroquine, quinacrine, quinide, phenothiazines, and diuretics Disorders such as hepatitis C Lichen planus - Health Diseases & Medical Conditions - AARP. Lichen Planus - NORD National Organization for Rare Disorders. Oral Lichen Planus Symptoms, Causes, and Treatment. The first choice for treatment of lichen planus is usually a prescription corticosteroid cream or ointment. If that doesn't help and your condition is severe or widespread, your doctor might suggest a corticosteroid pill or injection. When lichen planus develops in the mouth, it often does not cause pain or other symptoms. If this is the case, treatment may not be necessary. When lichen planus causes pain, burning, redness, blisters, sores, or ulcers, it can be treated. Some medicine is applied to the sores. Other medicine comes in pill form. Oral lichen planus is chronic and can be debilitating. Topical corticosteroids are most frequently used for treatment, but they are not always effective, Objective Hydroxychloroquine sulfate Plaquenil, an antimalarial agent, was evaluated in an open trial 10 patients for its ability to improve oral lichen planus.