Patients with suspected malaria should have parasitological confirmation of diagnosis with either microscopy or rapid diagnostic test (RDT) before antimalarial treatment is started. Treatment based on clinical grounds should only be given if diagnostic testing is not immediately accessible within 2 hours of patients presenting for treatment. Hydroxychloroquine dialysis Chloroquine pills Plaquenil help with fatigue Plaquenil malaria dose If species later identified as P. vivax or P. ovale, add primaquine or tafenoquine if not G6PD deficient by quantitative testing ‡Drug options for chloroquine-resistant P. falciparum may be used. Algorithm for Diagnosis and Treatment of Malaria * New Guinea or Indonesia should be treated with chloroquine, if patient does not respond, treatment should be changed to cover chloroquine-resistant P. vivax and CDC should be notified immediately Malaria Hotline number listed Chloroquine or hydroxychloroquine remains an effective choice for all P. vivax and P. ovale. infections except for P. vivax infections acquired in Papua New Guinea or Indonesia. The regimens listed for the treatment of P. falciparum are also effective and may be used. Malaria and, as no alternative to artemisinin derivatives is expected to enter the market for several years, their efficacy must be preserved. Prompt treatment – within 24 hours of fever onset – with an effective and safe antimalarial is necessary to effect a cure and prevent life-threatening complications. Vivax malaria treatment chloroquine Therapeutic efficacy of chloroquine for treatment of., Guidelines for Treatment of Malaria in the United States. Chloroquine inhibits autophagic flux by decreasing autophagosome lysosome fusion Chloroquine CQ continues to be the first-line medication used worldwide in the treatment of Plasmodium vivax malaria. The dose recommended by the World Health Organization is 25 mg/kg independently of the age of the subject. Evaluation of the paediatric dose of chloroquine in the.. Treatment of Malaria Guidelines for Clinicians. Mefloquine Dosage Guide with Precautions -. The recent drive to rid the world of malaria has brought P vivax to the fore, with the recognition that relapses pose a serious obstacle to its eradication, and with a recommendation that chloroquine and primaquine should be combined as a first-line treatment. However, primaquine, which can precipitate severe haemolysis in people with glucose-6-phosphate deficiency, is consequently often omitted or underdosed. Chloroquine is the ONLY drug used for P. vivax malaria, because resistance to chloroquine in P. vivax malaria is almost unknown in most countries. In most parts of the world, P. falciparum is resistant to chloroquine, and the recommended treatment is artemisinin bases combinations. Dec 24, 2015 Chloroquine CQ is the first-line treatment for vivax malaria in Ethiopia, but there is evidence for its declining efficacy. Defining the extent and regional distribution of CQ resistance is critical to ensure optimal treatment guidelines.