Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil causes dry eyes Plaquenil and mycophenolate Chloroquine method of action lysosome I was on the generic for less than a year and had to switch to the name brand because of intense itching and rashes. I did not realize the generic had Sulfa in it and I am allergic to Sulfa. No wonder! Also, after over two years of being on the name brand I had to get off it for the same allergic reaction. Are you sure that you are allergic to the Plaquenil. It seems very strange that you would be taking it with no problem and then all of a sudden have a reaction. An allergic reaction usually happens immediately after starting a drug or ingesting/coming into contact with an allergen. Plaquenil and Skin reaction - from FDA reports Summary Skin reaction is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Enbrel, and have Juvenile arthritis. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Allergic reaction from generic to plaquenil Hydroxychloroquine - Wikipedia, Allergic reaction to plaquenil DailyStrength Does plaquenil interact with prednisoneEvaluation while on hydroxychloroquine SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Will you have Skin reaction with Plaquenil - eHealthMe. Allergy to Plaquenil - Lupus - Inspire. Hydroxychloroquine is available as the brand-name drug Plaquenil. It’s also available in a generic version. Don’t take this drug again if you’ve ever had an allergic reaction to it. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Since the drug is cumulative in its effects you may be having an allergic reaction. My Father had the same reaction took him 3 weeks to develop it and he had to stop. It took 2 weeks for the rash to go away, but it was the Plaquenil. Now he's on Methotrexate and doing well.