Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil retinopathy screening guidelines 2011 Plaquenil for sjorens In fact, people with lupus should not smoke at all due to their increased risk of cardiovascular disease. Back to top. How to use Plaquenil. Lupus and/or rheumatoid arthritis patients will most likely take this medication by mouth, usually once or twice daily or as directed. Hydroxychloroquine generally is given to adults in doses of 200 mg or. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. How to tell if the drug is working. Re Plaquenil not working anymore Lizzy, I took 400mg 200 twice a day for 16-18 months forget exact duration, then was reduced to 200 mg daily. But right from the start, I also needed NSAID's for pain. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil not working anymore for lupus If Plaquenil doesn't work. Lupus Forums at The Lupus Site, Hydroxychloroquine Side Effects, Dosage, Uses, and More Plaquenil dosage for sjogrensPlaquenil sex driveHydroxychloroquine sulfate contraindicationsAralen for malaria prophylaxis Lupus-- also called systemic lupus erythematosus, or SLE -- might not have a cure, but it's a highly treatable condition. Lupus medications can help lower long-term risks and keep symptoms under. Lupus Medications and Treatments. Immune & Autoimmune - Lupus Plaquenil not working anymore. Plaquenil DailyStrength. Lupus and Plaquenil research. While Plaquenil was not created with the explicit purpose of helping people minimize the disease activity of lupus, a number of clinical trials have been conducted to examine the clinical impact of the medication. I'm on plaquenil now and was wondering when it wouldn't be enough anymore. My lupus has been a mixture of joints and inflammation around the heart and lungs. I was on quite the mix of drugs when I first started. Hopefully my lupus stays at this point for a long time, I'm not looking forward to my current meds not being enough. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis or juvenile idiopathic arthritis and other autoimmune diseases. It is not clear why hydroxychloroquine is effective at treating autoimmune diseases.