In a randomized, open-label, multicenter prophylaxis trial, 221 nonimmune pediatric travelers (age, 2–17 years) received either atovaquone-proguanil or chloroquine-proguanil. Safety and clinical outcome were evaluated 7, 28, and 60 days after travel. Chloroquine tablets nhs Plaquenil for seronegative arthritis Patent for proguanil chloroquine malaria Jun 15, 2004 Subsequently, 2 double-blind, controlled prophylaxis trials comparing the safety of atovaquone-proguanil with that of mefloquine and chloroquine plus proguanil hereafter, “chloroquine-proguanil” in nonimmune adults traveling to regions where malaria was endemic demonstrated that atovaquone-proguanil was associated with a lower frequency of treatment-related adverse events and of events leading to discontinuation of prophylaxis 13, 14. CONCLUSION Overall mefloquine is tolerated at least as well as chloroquine plus proguanil and shows better compliance, however, symptoms related to the central nervous system are more prevalent in mefloquine users and when symptoms develop, they are perceived as more severe. What Chloroquine & Proguanil Anti-Malarial Tablets contain. Chloroquine & Proguanil Anti-Malarial Tablets contain two types of tablets, chloroquine phosphate tablets and proguanil hydrochloride tablets. Chloroquine phosphate tablets The active substance is chloroquine phosphate. The data indicate that, over the course of treatment, fewer atovaquone-proguanil recipients had treatment-related adverse events (8% vs. Two subjects discontinued prophylaxis because of drug-related adverse events; both had received chloroquine-proguanil. By posttravel day 7, a total of 39 (35%) of 110 atovaquone-proguanil and 41 (37%) of 111 chloroquine-proguanil recipients reported ⩾1 adverse event. Chloroquine plus proguanil Medicines for the Prevention of Malaria While Traveling., Reported side effects to chloroquine, chloroquine plus. Aralen precioMonitoring hydroxychloroquine Atovaquone and Proguanil hydrochloride tablets are indicated for the prophylaxis of Plasmodium falciparum malaria, including in areas where chloroquine resistance has been reported. Atovaquone and Proguanil - FDA prescribing information.. Boots Chloroquine and Proguanil Anti-Malarial Tablets.. DailyMed - ATOVAQUONE AND PROGUANIL HYDROCHLORIDE tablet.. Find patient medical information for Atovaquone-Proguanil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Patient information for CHLOROQUINE AND PROGUANIL ANTI-MALARIAL TABLETS Including dosage instructions and possible side effects. Patient information for CHLOROQUINE AND PROGUANIL ANTI-MALARIAL TABLETS Including dosage instructions and possible side effects. • You are allergic to proguanil hydrochloride, chloroquine Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat.