Amiodarone, an antiarrhythmic, is the most common cause of corneal verticillata, followed by chloroquine, hydroxychloroquine, indomethacin, and phenothiazines. A comprehensive list of systemic drugs associated with corneal verticillata is given in . Neutropenia hydroxychloroquine Aralen online shopping Hydroxychloroquine sulfate and Abstral drug interaction Keratopathy -a study from FDA data Summary There is no Keratopathy reported by people who take Hydroxychloroquine sulfate and Abstral yet. Taking Hydroxychloroquine develop toxicity2 It’s rare for side effects to occur with Plaquenil if the medication is dosed properly Side effects Blurred vision, bull’s eye maculopathy, scotoma, vortex keratopathy, headache, accommodative dysfunction, whitening of eyelashes, phototoxicity3 Plaquenil hydroxychloroquine is an anti-malarial medication used to effectively treat rheumatoid arthritis and autoimmune conditions such as systemic lupus erythematosus and Sjögren’s Syndrome. Plaquenil is a drug that is stored in high concentrations throughout the body and is very slowly eliminated from the body. The deposits typically resolve with discontinuation of the responsible agents. It is unusual for these deposits to result in reduction of visual acuity or ocular symptoms, although this has occurred in some patients. Hydroxychloroquine keratopathy Cornea Verticillata - EyeWiki, Early Plaquenil Toxicity Detected without Bull’s Eye. Plaquenil corneal toxicityCan t afford plaquenilPlaquenil and humira interactionWhat does chloroquine treat Limitations of use Hydroxychloroquine is not effective against chloroquine- or hydroxychloroquine-resistant malaria strains of Plasmodium species; not recommended for treatment of complicated malaria, malaria prophylaxis in regions with chloroquine resistance, or treatment when the Plasmodium species has not been identified; hydroxychloroquine does not prevent relapses of P. vivax and P. ovale infections because it is not effective against the hypnozoite forms of these parasites. Hydroxychloroquine Professional Patient Advice -. PLAQUENIL hydroxychloroquine and the Eye Westford. Hydroxychloroquine - Wikipedia. Hydroxychloroquine keratopathy presents as an intraepithelial deposit. The deposits may take the form of whirls, linear opacities, or punctate lesions. Ciliary body dysfunction can be detected by poor near vision. Symptoms. In the initial stages of hydroxycloroquine toxicity, patients are often asymptomatic. Corneal verticillata, or vortex keratopathy, manifests as a whorl-like pattern of golden brown or gray deposits in the inferior interpalpebal portion of the cornea in a clockwise fashion Fig 12-15. A variety of medications bind with the cellular lipids of the basal epithelial layer of the cornea due to their cationic. Progression of vortex keratopathy VK causes increasing haloes and blur but is fully reversible upon discontinuation of therapy. Complications Even when the clinician and patient adhere to screening guidelines and retinopathy is detected in a sub-clinical stage, discontinuation of chloroquine or hydroxychloroquine therapy may not stop the progression of retinopathy to a stage where the patient loses vision.