Sulfasalazine hydroxychloroquine and methotrexate

Discussion in 'International Pharmacy' started by dim7, 03-Mar-2020.

  1. raul User

    Sulfasalazine hydroxychloroquine and methotrexate


    I've stopped Sulfa as I was experiencing a bad taste & smell, which may be caused by sulfa. After a while it wasn't as effective and I too was prescribed methotrexate alongside. I'm about to start MTX & am hoping that I wont have side effects with that! The side effects of the methotrexate for me were horrendous (chronic chest infections) and I'm now asthmatic as a result.

    Plaquenil 2016 Chloroquine phosphate ich

    Aug 22, 2006 O'Dell J R, Leff R, Paulsen G, Haire C, Mallek J, Eckhoff P J. et al Treatment of rheumatoid arthritis with methotrexate and hydroxychloroquine, methotrexate and sulfasalazine or a combination of the three medications results of a two year, randomized, double‐blind, placebo‐controlled trial. Arthritis Rheum 2002 46 1164–1170.1170 Methotrexate is one of the most durable and frequently used disease-modifying antirheumatic drugs DMARDs in monotherapy as well as the cornerstone of combination therapy for rheumatoid arthritis RA. Leflunomide, sulfasalazine, and hydroxychloroquine are effective therapies in RA and are commonly employed in combination therapy. Before the availability of drugs like methotrexate, damage to joints and related structures from chronic inflammation associated with RA was inevitable for many patients. 1. The most widely used traditional or conventional DMARDs include methotrexate, sulfasalazine Azulfidine ®, leflunomide Arava ®, and hydroxychloroquine Plaquenil.

    I had side effects from MTX, which largely wore off, but haven't had any problems with the Hydroxy or Sulpha. I refuse to take it now even if its my passport to biologic treatment. I started with MTX which worked, but not enough so the others were added in which has been better.

    Sulfasalazine hydroxychloroquine and methotrexate

    Management Considerations in Cancer Patients With., Traditional DMARDs Methotrexate, Leflunomide, Sulfasalazine.

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  4. I've been taking plaquenil, methotrexate and sulfasalazine for many years now. I was terrified to take mtx in the beginning, so I understand why you'd like to put that off for now. I did the same thing and tried plaquenil first.

    • Taking plaquenil and sulfasalazine Arthritis Information.
    • Traditional RA Disease modifying anti-rheumatic drugs.
    • Sulfasalazine and Hydroxychloroquine • Versus Arthritis..

    Traditional DMARDs Methotrexate, Leflunomide, Sulfasalazine, Hydroxychloroquine, and Combination Therapies Amy C. Cannella, James R. O’dell Key Points Methotrexate is one of the most durable and frequently used disease-modifying antirheumatic drugs DMARDs in monotherapy as well as the cornerstone of combination therapy for rheumatoid arthritis RA. Compare Methotrexate vs Sulfasalazine head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Methotrexate rated 6.7/10 vs Sulfasalazine rated 5.7/10 in overall patient satisfaction. Conventional DMARDs that have been paired with methotrexate include sulfasalazine, hydroxychloroquine, cyclosporine, leflunomide and azathioprine. Although studies of these combinations have shown differing levels of benefit, the combinations of methotrexate plus leflunomide and methotrexate plus sulfasalazine are among the most effective.

     
  5. dog43 Moderator

    There is so much misinformation out there on disease and parasite control in our hobby. Charlie Gregory of Healthy Aquatics Marine Institute, who specifically deals with fish and corals, to set the record straight and to start off a new series on the medicines that will effectively treat our fish. You can purchase the Chloroquine Diphosphate from New Life Spectrum in Amazon here. Chloroquine phosphate Chloroquine Phosphate REEF2REEF Saltwater and Reef Aquarium. Saltwater Aquarium Fish - Top 10 For Any Reef Tank.
     
  6. Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Hydroxychloroquine Oral Uses, Side Effects, Interactions. Hydroxychloroquine information booklet - Versus Arthritis Interactions between Travel Vaccines & Drugs - Chapter 2.
     
  7. Shatenka New Member

    Chloroquine - wikitox Chloroquine is a weak base and is slowly concentrated within cells by partitioning resulting in intracellular concentrations 60 fold higher than blood concentrations. The peripheral compartment has a Vd of about 200 L/kg and the terminal elimination half-life is 30-60 days. The drug crosses the placenta and is associated with foetal abnormalities.

    Volume of distribution - Wikipedia