While the exact percentage of RA patients who experience sleep problems is hard to nail down, more than 80% of people with RA report fatigue as part of their symptoms. Why Sleep Matters Sleep problems can increase levels of stress hormones and aggravate flares, says Rochelle Rosian, MD, a Cleveland Clinic rheumatologist. How does plaquenil treat lupus Hydroxychloroquine 200 mg for lupus Chloroquine diphosphate salt lysosome inhibitor Plaquenil has helped me on many levels on many days. I think, for me, anyway, the depression and anxiety I often feel is due to the autoimmune issues/sjogrens. I have not noticed an increase in depression/anxiety since being on the plaquenil but that is just me. View detailed reports from patients taking plaquenil who experienced insomnia. Reports are from official medical reports as well as online extractions from user reviews and forum discussions. Some medications, such as prednisone and hydroxychloroquine, also have the side effect of causing sleeplessness. It is a good idea to take these drugs earlier in the day to reduce this effect. “When you sleep, you make all those brain chemicals that you need to feel better. And even if you’re not flaring, you may not manage your pain as well if you’re not sleeping. Plaquenil and insomnia Plaquenil Uses, Dosage & Side Effects -, Hydroxychloroquine Sulfate Insomnia Reports - DrugInformer Plaquenil newbornCan apple cider vinegar be mixed with plaquenilMalaria hypnozoites resistant to chloroquinePlaquenil and cancer riskChloroquine and hydroxychloroquine for cancer therapy Treatment includes artificial tears and saliva and, in more severe cases, immune blockers such as prednisone, Plaquenil and even the cancer medication Methotrexate. Jacob Teitelbaum, MD. Print. Comments. The news has been buzzing about Venus Williams dropping out of the US Open because of Sjogren's syndrome. as the combination of insomnia. Why There's More to Sjogren's Syndrome The Dr. Oz Show. Rheumatoid arthritis and insomnia Tips for better sleep. Hydroxychloroquine-Induced Reversible Hypomnesis in a Patient.. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Description and Brand Names. Drug information provided by IBM Micromedex US Brand Name. Plaquenil; Descriptions. Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.