One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Plaquenil prsivribed by rheumatilogshrs cut in half Plaquenil leg pain Background and objectives Hydroxychloroquine is widely used in patients with rheumatoid arthritis. However, large-scale studies examining the long-term effects of hydroxychloroquine on the development of kidney disease in patients with rheumatoid arthritis are lacking. We aimed to assess the long-term association of hydroxychloroquine use with the risk of developing CKD in this population. Hydoxychloroquine HCQ is widely used for the treatment of rheumatoid arthritis RA and systemic lupus erythematosus SLE with a side-effect profile including myopathy and cardiotoxicity. Acute HCQ poisoning has been reported to cause a prolonged QT interval, hypokalaemia and a prolonged QRS complex. Mar 17, 2019 Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Hydroxychloroquine widely use Stevens–Johnson syndrome in association with., Long QT and Hydroxychloroquine; A Poorly Recognised Problem. Symptoms of ete damage when taking hydroxychloroquine Mechanism of action of hydroxychloroquine as an antirheumatic drug. Fox RI1. Author information 1Department of Rheumatology, Scripps Clinic and Research Foundation, La Jolla, CA 92037. The antimalarial agents chloroquine and hydroxychloroquine have been used widely for the treatment of rheumatoid arthritis and systemic lupus erythematosus. Mechanism of action of hydroxychloroquine as an antirheumatic.. Hydroxychloroquine Uses, Dosage & Side Effects -. Hydroxychloroquine Oral Uses, Side Effects, Interactions.. U. S. researchers, following the lead of scientists in other countries, have launched studies to see whether widely-available, low-cost generic drugs can be used to help treat the illness caused by. Mar 04, 2020 Hydroxychloroquine or Plaquenil It is commonly used to treat various complications as a result of lupus and other connective tissue disorders; that is to say, the set of cells of the organism that has the same function and that constitute the fundamental structure of the different organs of the human body. Uses of Hydroxychloroquine or Plaquenil Aug 25, 2019 Commonly used on holidays in malaria prone destinations, chloroquine and hydroxychloroquine will not be over familiar to the emergency physician. However, it is one of the leading causes of drug overdose in malaria prone countries and also the occasional toddler has managed to consume the grandparents lupus or rheumatoid arthritis medication leading to lethal consequences.