It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Hydroxychloroquine formulation availability Hydroxychloroquine metabolism Plaquenil and turmeric Plaquenil for sickle cell anemia Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. We compare the side effects and drug effectiveness of Plaquenil and Methotrexate. The study is created by eHealthMe based on reports of 385,604 people who take Plaquenil and Methotrexate, and is updated regularly. eHealthMe has been monitoring drugs since 2008. Our original studies are referenced on 600+ peer-reviewed medical publications. Call your doctor immediately or get emergency medical help if you experience any of the following serious side effects Any vision problems, such as reading difficulties, sensitivity to light, seeing light flashes or streaks, blurred distance vision, or other issues Hearing problems. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Side effects of plaquenil and methotrexate Methotrexate and plaquenil - @Kristinsaba1988., Plaquenil vs. Methotrexate side effect and effectiveness. Chloroquine and g6pdCan plaquenil cause alopecia GI problems such as nausea and vomiting are the most common side effects associated with methotrexate, affecting between 20and 65 percent of RA patients who take the drug. While hair loss is a relatively uncommon side effect in patients who take methotrexate at such doses, up to one third develop mouth ulcers, or sores. Side effects plaquenil/methotrexate. rheumatoid. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Compare Methotrexate vs Plaquenil -. Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and. Prescribed for Lyme Disease - Arthritis, Dermatomyositis, Malaria Prevention, Malaria, Rheumatoid Arthritis. Side-effects aren't common. However, in some people hydroxychloroquine can cause skin rashes, especially those made worse by sunlight; feeling sick nausea or indigestion; diarrhoea; headaches; bleaching of the hair or mild hair loss; tinnitus ringing in the ears visual problems. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember.