Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking chloroquine: Incidence not known Some side effects of chloroquine may occur that usually do not need medical attention. Chloroquine toxicity cells How soon does hydroxychloroquine work Plaquenil dose availability Can hydroxychloroquine cause high blood glucose levels Diagnosis of cardiomyopathy can be difficult due to the lack of specificity of symptoms and concurrent cardiovascular involvement of the underlying disease 3. When detected early, hydroxychloroquine induced cardiomyopathy may be reversible 4. Therefore, patients requiring long-term therapy should be appropriately monitored. Chloroquine-Induced Cardiomyopathy In this case, vacuolated cardiomyocytes and curvilinear body formation were observed on light and electron micros-copy, respectively, which are pathognomic findings of the intralysosomal accumulation of lipids. Cervera et al.1 recom-mended that a cardiac evaluation with an ECG and an oph- Electron microscopy of the myocytes demonstrated dense, myeloid, and curvilinear bodies. The diagnosis of hydroxychloroquine-induced cardiomyopathy was made based on the clinical, hemodynamic, and pathologic findings. This is the first case report describing chloroquine-induced cardiomyopathy involving the heart conduction system. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Chloroquine induced cardiomyopathy Hydroxychloroquine-Induced Restrictive Cardiomyopathy in a., A Case of Chloroquine-Induced Cardiomyopathy That. Treatment of cerebral malaria chloroquine In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. A Case of Chloroquine-Induced Cardiomyopathy That Presented.. Hydroxychloroquine-induced cardiomyopathy case report.. The findings of CMR and light microscopy ruled out all these diagnoses except for Fabry disease, which is a vacuolar cardiomyopathy very similar to chloroquine-induced cardiomyopathy, and which can be distinguished by TEM findings as discussed below. To the Editor Chloroquine CQ has been used for the treatment and prophylaxis of malaria since World War II. Ten years later, the administration of CQ and hydroxychloroquine HCQ was introduced for the longterm therapy of rheumatic diseases. Although no reliable statistical data are available, HCQ, which differs from CQ only in a hydroxyl group at the end of the side chain, but not in. Hydroxychloroquine and colchicine neuromuscular toxicity is well documented. The largest literature review on colchicine myopathy was conducted by Wilbur and Makowsky in 2004 where a database search found 75 cases. Most patients presented with proximal muscle weakness. A wide range of treatment durations were noted from 4 days to 11 yrs with cumulative daily doses of 1.4 ± 0.96 mg. The.