Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Maculopathy hydroxychloroquine Plaquenil and allergy testing Plaquenil headache Plaquenil treatment Hydroxychloroquine oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. May 13, 2009 Other studies have reported that HCQ is safe to use during pregnancy but had no control group 35-40. All 4 of the studies 27 - 30 assessed the presence of congenital defects in babies born to women with autoimmune diseases Additional file 1, Table S2 and Figure Figure2a. 2a. Hydroxychloroquine and prednisone are considered safe during pregnancy. Methotrexate and cyclophosphamide Cytoxan should not be used in pregnancy and should be discontinued for at least a. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Is hydroxychloroquine safe to take during pregnancy Treatment of SLE in pregnancy and use of Chloroquine The BMJ, Systematic review of hydroxychloroquine use in pregnant. Chloroquine poisoning The use of HCQ during pregnancy has long been debated, but nowadays, consensus is reached that it is safe and it is frequently prescribed during pregnancy to diminish flares 2, 3. However, reports on the detailed effects of HCQ on pregnancy outcomes are scarce and mostly focus on teratogenicity. Hydroxychloroquine Use in Lupus Patients during Pregnancy.. Lupus and Pregnancy Tips for Living with Lupus. Is Hydroxychloroquine Safe to Use During Pregnancy?. OBJECTIVE The use of hydroxychloroquine HCQ in pregnancy remains controversial. The recent demonstration that HCQ passes across the placenta, with cord blood concentrations nearly identical to those found in maternal blood, emphasizes the need for careful evaluation of pregnancies in women receiving HCQ. Continue taking the medicine regularly during your stay and for at least 8 weeks after you leave the area. To treat malaria Hydroxychloroquine is usually given for 3 days, starting with one high dose followed by a smaller dose during the next 2 days in a row. Hydroxychloroquine is usually considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are not known. Talk to your healthcare provider about the risks and benefits of using hydroxychloroquine during pregnancy see Plaquenil and Pregnancy for more information.