Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Hair loss caused by plaquenil Plaquenil sjogren's fatigue Does chloroquine decrease potassium levels View interaction reports for hydroxychloroquine and the medicines listed below. Advil ibuprofen Aleve naproxen amitriptyline. amoxicillin. aspirin. Aspirin Low Strength aspirin Benadryl diphenhydramine Plaquenil’s long half-life in the body can cause irreversible and progressive damage, Dr. Fung said. Similarly, one study reported that 16 women who’d taken hydroxychloroquine or chloroquine, or a combination of the agents, showed no improvement seven years after stopping drug therapy, and progression occurred in six of the cases. 2 Plaquenil Hydroxychloroquine belongs to a group of medications known as anti-inflammatories and antimalarials. It is used alone or in combination with other anti-arthritic medications to treat rheumatoid arthritis. It helps to reduce pain, stiffness, and swelling in joints. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Plaquenil and coumadin interaction Acetaminophen and Warfarin The Forgotten Interaction, Rx Side Effects New Plaquenil Guidelines and More - American Academy. Chloroquine sp combinationDefine hydroxychloroquineOther names for chloroquineRetinal exam hydroxychloroquine frequency Digoxin, cyclosporine, and certain beta blockers may cause drug interactions with hydroxychloroquine. This eMedTV segment explores what may happen if these drugs are taken with hydroxychloroquine and lists other drugs that may cause an interaction. Drug Interactions With Hydroxychloroquine. Plaquenil - Uses, Side Effects, Interactions -. Plaquenil Oral Interactions with Other Medication. The following sections explain in detail the potentially negative interactions that can occur when Plaquenil is combined with any of the drugs listed above. Certain Beta Blockers Plaquenil may increase the level of some but not all beta blockers in the blood, perhaps increasing the risk of side effects. Today, Plaquenil and other antimalarials are also used to treat and help prevent symptoms caused by certain autoimmune diseases such as rheumatoid arthritis RA, systemic lupus erythematosus, and discoid lupus, even though these diseases are not caused by malaria parasites. Minerals and Drug Interactions Calcium Calcium is a mineral supplement taken primarily to prevent or treat osteoporosis. It is found in dairy products and is available as a supplement or as a component of some antacids, such as Tums.