Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil and neutropenia Chloroquine cancer clinical trials Plaquenil common side effects Chloroquine lysosomal membrane permeabilization Check with your doctor immediately if any of the following side effects occur Incidence not known. Blistering, peeling, loosening of the skin blurred vision or other vision changes chest discomfort, pain, or tightness cough or hoarseness dark urine decreased urination defective color vision diarrhea difficulty breathing The only side effects from Plaquenil that most of us notice is possibly an upset stomach for a few days.sure to take with food. Depression, anxiety, and brain fog could be Lupus symptoms -- or they could be from Remicade, I'm not familiar with it's side effects. Mar 03, 2016 The only major side effect, and it is major, is that sometimes in can build up in the eye and damage vision. But it is something they can catch easily. I had to have a baseline image of my eyes with a kind of fluoroscope before starting the Plaquenil. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Side effects plaquenil forums Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Plaquenil - Lupus Plaquenil adverse effect on retinaHow does chloroquine workPlaquenil bradycardiaPlaquenil retina damage More in Eye Health. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Plaquenil Side Effects on Your Eyes and Vision. Plaquenil - how long for side effects to subside?. Plaquenil side effects" Lupus Community - Support Group. Plaquenil hydroxychloroquine "I've been on a roller coaster for yrs w/Plaquenil for RA/Lupus. I take name brand to prevent side effects of red, warm, swollen, painful hands + nausea/dizziness, hair loss, etc. Rheumatoid arthritis and was immediately placed on Plaquenil. I agree that it is a relatively benign drug, insofar as immediate side effects are concerned. Stomach problems, if they exist, can be easily combated with Rinitidine. However, the one side effect that can and does happen, quite often, is retinal damage. Apr 16, 2017 The worst side effects for me are hot flashes/chills/night sweats and extreme moodiness. I'd like to know if anyone here has had these side effects and if they went away over time, and if so, how long it took. Or, in general, how long it takes for side effects with Plaquenil to get better, if they do at all.