It regulates the activity of the immune system, which may be overactive in some conditions. Hydroxychloroquine can modify the underlying disease process, rather than simply treating the symptoms. Can you take plaquenil and unithroid Plaquenil for plaque Methotrexate trexall and hydroxychloroquine plaquenil Mar 24, 2011 Had headaches with the plaquenil so went to the sulfar and predisone. Sulfar was a waste of time and since I had a little help from the plaquenil he switched me back to that with pain meds for the headaches and body. Recently i went back for app. and plaquenil had stopped doing anything so he added the methotrexate to it. I did not want to take it. Re Plaquenil - Can It Work Quickly? I tried to get on Plaquenil years ago, and couldn't tolerate it, but now I'm thinking there might be a lessor dose I should try. I'm new to the area, so don't have a rheumy yet. User Reviews for Plaquenil to treat Rheumatoid Arthritis. The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. Hydroxychloroquine is often taken in combination with other drugs such as methotrexate. Over the long term hydroxychloroquine can reduce pain, swelling and joint stiffness. It may be as long as 12 weeks before you notice the benefits. Plaquenil how does it work Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus, Immune & Autoimmune - Lupus Plaquenil - Can It Work Quickly? Pics of ocular side effects chloroquine corneal damagePlaquenil and omeprazole Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria chloroquine-resistant. The United States Center for. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Plaquenil User Reviews for Rheumatoid Arthritis at. Plaquenil hydroxychloroquine. Plaquenil changes the way your immune system works. In some kinds of lupus, your immune system attacks your body instead of protecting it. Plaquenil tries to quiet or slow down the immune system. Last week my doc added plaquenil to the mix. I have a pharmacist friend that says it can take up to a year to work, but once its kicks in it can be really good. I suggest you ask your rhuemie for additional help in the meantime. I have had RA going on 12 years, and originally way back when I ws given plaquenil alone and it did nothing. Plaquenil is also an option for those who try and fail biologic drugs, cannot tolerate biologics or fear potential side effects linked to biologic DMARDs. How It Works Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability.