Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. How do i know if i'm allergic to hydroxychloroquine Nifedipine and hydroxy chloroquine Plaquenil side effects gas Oct 01, 2018 It is recommended that Chloroquine be discontinued if ocular toxicity is suspected and the patient should be closely observed given that retinal changes and visual disturbances may progress even after cessation of therapy. Central Nervous System Effects Ocular side effects Hydroxychloroquine can cause irreversible retinal toxicity, resulting in bilateral bull’s eye retinopathy, but is regarded as less toxic to the retina than chloroquine and it does not cause the corneal deposits seen with chloroquine therapy. Specifically it is used for chloroquine -sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Common side effects include vomiting, headache, changes in vision and muscle weakness. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Ocular side effects of chloroquine therapy Ocular side effects of chloroquine treatment of rheumatoid., Hydroxychloroquine DermNet NZ Hydroxychloroquine or sulfasalazine Ocular complications of rheumatological therapies may relate to 1 direct drug-specific toxic effects, such as chloroquine retinopathy, 2 indirect drug-specific side-effects, such as corticosteroid-induced ocular hypertension resulting in secondary glaucoma, and 3 drug non-specific complications relating to immunosuppression, such as opportunistic infections. Chloroquine Retinopathy - an overview ScienceDirect Topics. Hydroxychloroquine - Wikipedia. Chloroquine Side Effects Common, Severe, Long Term -. Chloroquine has also been tested in clinical trials as an antiretroviral agent against HIV and as a radiosensitizer and chemosensitizer for human cancer therapy. However, the side effects of Chloroquine, including ocular toxicities, limit its long-term use 2-4,6. What are the ocular side effects and risks of chloroquine? Corneal deposits. Corneal deposits occur rapidly in 90% of patients on chloroquine. Retinal toxicity. Irreversible retinal toxicity, causing bilateral bull’s eye retinopathy. Screening recommendations. Every patient planning to take. A severe eye problem has happened with chloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years.