It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Is plaquenil porcine based How plaquenil helps lupus reviews How long for plaquenil rash to end - I started plaquenil in January and I started with a severe rash covered about 70% of body in May. My Rheumy had me stop taking plaquenil after 1 week of the rash getting worse. After that it took about another 2-3 weeks for it to be totally cleared up. He said it had to work How long does it take for imuran and plaquenil hydroxychloroquine to completely leave your system if you stop them after taking thrm for 1 month. 4 doctors weighed in Dr. William Lages Plaquenil is a slow acting drug. It can take up to 6 months for full effectiveness. So give it time. Most people, however, notice some improvement after about two months. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. How long do plaquenil stay in your system Long-term effects of plaquenil - Doctor answers on., How long does it take for imuran and plaquenil. Chloroquine derived fromHyperprolactinemia caused by chloroquineCan swollen ankles be caused by hydroxychloroquineHydroxychloroquine and ccca alopecia In response to the original question, 60 to 90 days, as long as it take to become effective. As far as panic attacks and side effects are concerned, I have been on it for nine months and the first two weeks are less than comfortable nausea, change in taste, ringing in your ears, hot and cold flashes are completely typical. How long does it take for plaquenil to leave your system?. Plaquenil Hydroxychloroquine for use in Autoimmune.. What happens if I stop taking plaquenil hydroxychloroquine.. This means that every 32 days, half of the previous amount of hydroxychloroquine in the body disappears. It takes around 5.5 half lives for a drug to be completely eliminated from your body meaning that you may need to wait for around 176 days. I say this because Plaquenil has a chemical half-life of 30-60 days you can confirm this on wiki or RX info on the drug--so it takes a LONG time to get out of your system.long for you to notice changes in days. If you remember, most wait at least 3 months before they even see any improvement. The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. It's important to watch for possible side effects and toxicity.