I don't get many side effects generally, but with prednisone I DO. It does help, but this can't be a long term affair. Plaquenil is a great drug (I have no experience with it, but many people with lupus take it). I'd ask your rheumy about it and have them explain why they made that choice for you. Prednisone is an intermediate acting corticosteroid-which means it has direct anti-inflamitory properties that take effect begining in a few hours. Is plaquenil another option instead of the prednisone? It is ment to get this undercontrol now and diminish your pain. Chloroquine purpose Is chloroquine safe during pregnancy Hydroxychloroquine prasco labs Hair loss side effects plaquenil Take hydroxychloroquine for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared. When treating lupus or arthritis, tell your doctor if your symptoms do not improve after 6 months of treatment. Before taking this medicine. You should not use hydroxychloroquine if you are allergic. You must also make sure to taper EXACTLY as directed by your doctor as not doing so can cause serious issues. If you are having joint pain/inflammation and kidney issues then you should take the prednisone now and continue in confirming your diagnosis of Lupus. As for the plaquenil, this is an 'old school' treatment of Lupus. Medical treatment for lupus has made great strides within the last 50 years. This article will help you understand lupus treatments, lupus medications and side effects, and important lifestyle. It has not direct anti-inflamitory properties and instead works on the immune system-though the mechanism is not known. Plaq is a longer time medication it may take two months before their is a noticable difference. Should you take plaquenil with steroids , Danger in taking Plaquenil and Prednisone if its not Lupus. Chloroquine nail changesVivax malaria treatment chloroquinePlaquenil 100 mgHydroxychloroquine withdrawal Dec 15, 2010 hello hope everyone is well just a quick question, i have been on methotrexate for 2 months increasing from 7.5 to 15 and now to 25mg.weekly now been given plaquenil 400mg daily, has anyone else been on this mixture and has it worked or how long should i wait to see if it works. Methotrexate and plaquenil -. Lupus Medications and Treatments. Protecting your eyesight when taking Plaquenil Lupus.. One Plaquenil tablet contains 200 mg of hydroxychloroquine sulfate, which is equivalent to 155 mg base. Take Plaquenil with a meal or a glass of milk. Malaria. Prophylaxis Adults 400 mg 310 mg base once weekly on the same day of each week starting 2 weeks prior to exposure, and continued for 4 weeks after leaving the endemic area. Nov 11, 2019 Additionally, high-dosage or prolonged use of prednisone may reduce the immune response to certain vaccines and make them less effective. If you have been heavily treated with prednisone, you should wait for at least three months after stopping before getting a live vaccine. Compare Plaquenil vs. Prednisone, which is better for uses like Lupus, RA and Sjogren's Syndrome. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Patients rated Plaquenil 3.7/5 over Prednisone 3.2/5 in overall satisfaction.