It is similar to CQ in practically any way, although its similar efficacy against COVID-19 would still be an assumption. So far I have found these: There are about 10 clinical trials in China looking at hydroxychloroquine for COVID, including some comparing it with chloroquine phosphate. Chloroquine as antiamoebic What is hydroxychloroquine generic for Plaquenil dental contraindications Hydroxychloroquine cause urinary infections Chloroquine has a high affinity for tissues of the parasite and is concentrated in its cytoplasm. As a weak base, it increases the pH of the intracellular lysosome and endosome. A more acidic medium in these organelles is needed for the parasite to affect mammalian cells. As a result, chloroquine inhibits growth and development of parasites. Hydroxychloroquine has a lower risk of ocular toxicity, both corneal and retinal, compared with chloroquine. Smoking possibly reduces the efficacy of hydroxychloroquine, although studies have not usually confirmed this clinical impression. Hydroxychloroquine is considered safer than chloroquine during pregnancy and lactation. The usual adult dose for treating malaria is 800 mg initially, followed by 400 mg 6-8 hours later and then 400 mg at 24 hours and 48 hours. The dose for malaria prevention is 400 mg every week starting 1 or 2 weeks before exposure and for 4 weeks after leaving the high risk area. You can search the Chinese clinical trial database here (type "hydroxychloroquine" into the Public Title field): HCQ prevents dengue virus infection in vitro. Don't worry, the studies are being done and the data will be out soon. Chloroquine major issue Chloroquine Phosphate – Marine Fish Diseases and Treatment, Hydroxychloroquine DermNet NZ Hydroxychloroquine can suppress appetite Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Hydroxychloroquine Side Effects Common, Severe, Long Term -. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Aquarium Fish Chloroquine A "New" Drug for Treating Fish Diseases.. Chloroquine is a 4-aminoquinoline with antimalarial, anti-inflammatory, and potential chemosensitization and radiosensitization activities. Although the mechanism is not well understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. Aralen chloroquine is an antimalarial drug used for the treatment of malaria and extraintestinal amebiasis. Common side effects are reduced hearing, tinnitus, nausea, vomiting, and diarrhea. Dosage, drug interactions, and pregnancy and breastfeeding safety are provided. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. Occasionally it is used for amebiasis that is occurring outside the intestines, rheumatoid arthritis, and lupus erythematosus.