Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Show me a picture of hydroxychloroquine Reducing plaquenil Side-effects and risks. Side-effects aren't common. However, in some people hydroxychloroquine can cause skin rashes, especially those made worse by sunlight. feeling sick nausea or indigestion. diarrhoea. headaches. bleaching of the hair or mild hair loss. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Common side effects include vomiting, headache, changes in vision and muscle weakness. Severe side effects may include allergic reactions. It appears to be safe in pregnancy but this use has not been well studied. Hydroxychloroquine is in the antimalarial and 4-aminoquinoline families of medication. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Hydroxychloroquine side effects kidney RA and Hydroxychloroquine How Effective is it for Rheumatoid., Hydroxychloroquine Plaquenil Compound drug for plaquenilHow to take hydroxychloroquine Serious side effects. blurred vision or other vision changes. ringing in your ears or hearing loss. angioedema, or rapid swelling of your skin. hives. mild or severe bronchospasm that causes trouble breathing. sore throat. unusual bleeding or bruising. blue-black skin color. muscle weakness. hair. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Hydroxychloroquine - Wikipedia. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Risk of Chronic Kidney Disease in Rheumatoid Arthritis Patients. Hydroxychloroquine, is one of the widely used drugs to treat rheumatoid arthritis. However, the documentation of long-term effects of hydroxychloroquine was lacking in meeting these criteria; a study was conducted by Prof. Der-Cherng Tarng and his team. Get medical help right away if you have any very serious side effects, including sensitivity to light, vision changes e.g. blurred vision, seeing light flashes/streaks/halos, missing/blacked-out areas of vision, muscle weakness, numbness/tingling/pain of the arms/legs. Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.