Resistance to currently available antimalarial drugs has been confirmed in only two of the four human malaria parasite species, first developed independently in three to four areas in Southeast Asia, Oceania, and South America in the late 1950s and early 1960s. Since then, chloroquine resistance has spread to nearly all areas of the world where falciparum malaria is transmitted. Chloroquine doxycycline Hydroxychloroquine combination Hydroxychloroquine routine diagnostics Cost plaquenil thru prime therapeutics Facts about malaria in Nigeria. In Nigeria, malaria is endemic. Accounts for 60% of outpatient visits. Responsible for 30% of under-5 mortality. Resurgence of malaria is observed in recent times. Resurgence due to increasing resistance to chloroquine & sulfadoxine-pyrimethamine. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. It is also occasionally used for amebiasis that is occurring outside the intestines, rheumatoid arthritis, and lupus erythematosus. It is taken by mouth. Common side effects include muscle problems, loss of appetite, diarrhea, and skin rash. Serious Chloroquine resistance of Plasmodium falciparum is associated with severity of disease in Nigerian children Although resistance to these drugs tends to be much less widespread geographically, in some areas of the world, the impact of multi-drug resistant malaria can be extensive. Has also developed resistance to nearly all of the other currently available antimalarial drugs, such as sulfadoxine/pyrimethamine, mefloquine, halofantrine, and quinine. Nigeria malaria chloroquine resistance Coronavirus Nigeria reports chloroquine poisonings after., Chloroquine - Wikipedia Multifocal erg and plaquenilHydroxychloroquine sulfate costPlaquenil 25 mg Chloroquine was the main drug used in treatment of malaria throughout the periods studied, with frequency of prescription at both sites ranging from 91.4% to 98.3% during the pre-resistance years. It was administered as standard doses during the pre resistance years. Anti-histamines, especially promethazine. Potential contribution of prescription. - Malaria Journal. Chloroquine resistance of Plasmodium falciparum is.. Nigeria Malaria Fact Sheet - State. May 01, 2018 Unchecked, insecticide resistance could lead to a substantial increase in malaria incidence and mortality. The global malaria community and for that matter, Nigeria, needs to take urgent action to prevent an increase in insecticide resistance, and to maintain the effectiveness of existing vector-control interventions. Chloroquine was banned as a first line treatment drug for malaria in Nigeria in 2005. The decision, based on the recommendation of the World Health Organisation, was taken by the Federal Ministry. Chloroquine was in use for more than 50 years before misuse and adulteration led to development of resistance by the malaria parasite and subsequent ban of the drug by the World Health Organisation.