Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Does plaquenil help psoriatic arthritis Chloroquine systemic lupus erythematosus Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Find information about common, infrequent and rare side effects of Plaquenil Oral. Plaquenil side effects Get emergency medical help if you have signs of an allergic reaction to Plaquenil hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil teeth side effects Hydroxychloroquine Oral Uses, Side Effects, Interactions., Common and Rare Side Effects for Plaquenil Oral Chloroquine effect on cell lysisHydroxychloroquine sulfate tabs 200mgIs chloroquine a lysosome Find information about common, infrequent and rare side effects of Methotrexate Anti-Rheumatic Oral. Common and Rare Side Effects for Methotrexate Anti.. Plaquenil Uses, Dosage & Side Effects -. Common Plaquenil side effects a study from FDA data - eHealthMe. Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. The side effect that is of greatest concern is retinal toxicity. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about.