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The dose is usually taken 1 hour before sexual activity. read more They need to know if you have any of these conditions: -bleeding disorders -eye or vision problems, including a rare inherited eye disease called retinitis pigmentosa -anatomical deformation of the penis, Peyronie's disease, or history of priapism (painful and prolonged erection) -heart disease, angina, a history of heart attack, irregular heart beats, or other heart problems -high or low blood pressure -history of blood diseases, like sickle cell anemia or leukemia -history of stomach bleeding -kidney disease -liver disease -stroke -an unusual or allergic reaction to vardenafil, other medicines, foods, dyes, or preservatives -pregnant or trying to get pregnant -breast-feeding Take this medicine by mouth with a glass of water. You should not take this dose more than once per day. Do not take your medicine more often than directed. Do not take this medicine with any of the following medications: -bepridil -certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole -cisapride -droperidol -grepafloxacin -medicines for irregular heartbeat like dronedarone, dofetilide -methscopolamine nitrate -nitrates like amyl nitrite, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin -nitroprusside -other medicines for erectile dysfunction like avanafil, sildenafil, tadalafil -pimozide -riociguat -thioridazine -ziprasidone This medicine may also interact with the following medications: -antiviral medicines for HIV or AIDS -certain antibiotics like erythromycin and clarithromycin -certain drugs for high blood pressure -medicines for prostate problems -other medicines that prolong the QT interval (cause an abnormal heart rhythm) This list may not describe all possible interactions. Talk to your pediatrician regarding the use of this medicine in children. Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. If you notice any changes in your vision while taking this drug, call your doctor or health care professional as soon as possible. Stop using this medicine and call your health care provider right away if you have a loss of sight in one or both eyes. Contact your doctor or health care professional right away if the erection lasts longer than 4 hours or if it becomes painful. 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